USP47在慢性粒细胞性白血病发病和治疗中的作用和机制
81570118
2015
H0809.白血病
吴英理
面上项目
教授
上海交通大学
60万元
去泛素化蛋白酶47;慢性粒细胞白血病;BCR/ABL;去泛素化蛋白酶;信号转导和转录激活因子5
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Isobavachalcone reveals novel characteristics of methuosis-like cell death in leukemia cells | 期刊论文 | Yang Li;Song Lili;Zhao Shan;Ma Chunmin;Wu Depei;Wu Ying Li |
| 2 | USP47 Is a New Target in Chronic Myelogenous Leukemia | 会议论文 | Lei Hu;Ma Chunmin;Liu Zhen;Gao Shenmeng;Zhou Li;Wang Weiwei;Xu Hanzhang;Gao Fenghou;Wu Yingli;Liu Han |
| 3 | Sinomenine derivative YL064: a novel STAT3 inhibitor with promising anti-myeloma activity. | 期刊论文 | Wang Yingying;Wu Linlin;Cai Haiyan;Lei Hu;Ma Chun-Min;Yang Li;Xu Hanzhang;Zhu Qi;Yao Zhujun;Wu Yingli |
| 4 | Chk1 inhibitors overcome imatinib resistance in chronic myeloid leukemia cells. | 期刊论文 | Lei Hu;Jin Jin;Liu Meng;Li Xiangyun;Luo Hao;Yang Li;Xu Hanzhang;Wu Yingli |
| 5 | Characterization of naturally occurring pentacyclic triterpenes as novel inhibitors of deubiquitinating protease USP7 with anticancer activity in vitro. | 期刊论文 | Jing Bo;Liu Meng;Yang Li;Cai Hai-Yan;Chen Jie-Bo;Li Ze-Xi;Kou Xi;Wu Yun-Zhao;Qin Dong-Jun;Zhou Li;Jin Jin;Lei Hu;Xu Han-Zhang;Wang Wei-Wei;Wu Ying-Li |
| 6 | MK2206 enhances the cytocidal effects of bufalin in multiple myeloma by inhibiting the AKT/mTOR pathway | 期刊论文 | Xiang Rufang;Wang Yan;Zhang Nan;Xu Wenbin;Cao Yang;Tong Jia;Li Junmin;Wu Yingli;Yan Hua |
| 7 | Overexpression of Fbxo6 inactivates spindle checkpoint by interacting with Mad2 and BubR1. | 期刊论文 | Xu Han-Zhang;Wang Zhuo-Qun;Shan Hui-Zhuang;Zhou Li;Yang Li;Lei Hu;Liu Bin;Wu Ying-Li |
| 8 | USP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemia. | 期刊论文 | Shan Huizhuang;Li Xiangyun;Xiao Xinhua;Dai Yuting;Huang Jinyan;Song Junjun;Liu Meng;Yang Li;Lei Hu;Tong Yin;Zhou Li;Xu Hanzhang;Wu Yingli |
| 9 | Quinacrine Depletes BCR-ABL and Suppresses Ph-Positive Leukemia Cells | 期刊论文 | Lei Hu;Tu Yaoyao;Yang Li;Jin Jin;Luo Hao;Xu Hanzhang;Kang Jingwu;Zhou Li;Wu Yingli |
| 10 | A novel “mosaic-type” nanoparticle for selective drug-release targeting hypoxia cancer cells | 期刊论文 | Wang W;Li XY;Wang ZH;Zhang J;Wu YZ;Dong X;Fang C;Zhou AW;Wu YL |
| 11 | Vorinostat and quinacrine have synergistic effects in T-cell acute lymphoblastic leukemia through reactive oxygen species increase and mitophagy inhibition. | 期刊论文 | Jing Bo;Jin Jin;Xiang Rufang;Liu Meng;Yang Li;Tong Yin;Xiao Xinhua;Lei Hu;Liu Wei;Xu Hanzhang;Deng Jiong;Zhou Li;Wu Yingli |
| 12 | Targeting deubiquitinating enzymes in cancer stem cells | 期刊论文 | Lei Hu;Shan Huizhuang;Wu Yingli |
| 13 | Montelukast inhibits hypoxia inducible factor-1alpha translation in prostate cancer cells. | 期刊论文 | Tang Caixia;Lei Hu;Zhang Jinfu;Liu Meng;Jin Jin;Luo Hao;Xu Hanzhang;Wu Yingli |
| 14 | Targeting oncoproteins for degradation by small molecules in myeloid leukemia. | 期刊论文 | Lei Hu;Wang Weiwei;Wu Yingli |
| 15 | Identification of 11(13)-dehydroivaxillin as a potent therapeutic agent against non-Hodgkin's lymphoma | 期刊论文 | Xiao Xinhua;Li Huiliang;Jin Huizi;Jin Jin;Yu Miao;Ma Chunmin;Tong Yin;Zhou Li;Lei Hu;Xu Hanzhang;Zhang Weidong;Liu Wei;Wu Yingli |
| 16 | WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia | 期刊论文 | Luo Hao;Jing Bo;Xia Yu;Zhang Yugen;Hu Meng;Cai Haiyan;Tong Yin;Zhou Li;Yang Li;Yang Junmei;Lei Hu;Xu Hanzhang;Liu Chuanxu;Wu Yingli |
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