Quinacrine靶向下调慢性髓性白血病中BCR-ABL蛋白的分子机制研究
81570112
2015
H0808.骨髓增殖性肿瘤
周励
面上项目
副主任医师
上海交通大学
60万元
耐药;BCR-ABL;慢性髓性白血病;酪氨酸激酶抑制剂;Quinacrine
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 国产伊马替尼治疗慢性髓性白血病的血药浓度与疗效分析 | 期刊论文 | 游建华;陈娟;周励;杜圣红;卢虹颖;孙舒君;李军民;沈志祥 |
| 2 | WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia | 期刊论文 | Luo Hao;Jing Bo;Xia Yu;Zhang Yugen;Hu Meng;Cai Haiyan;Tong Yin;Zhou Li;Yang Li;Yang Junmei;Lei Hu;Xu Hanzhang;Liu Chuanxu;Wu Yingli |
| 3 | Characterization of naturally occurring pentacyclic triterpenes as novel inhibitors of deubiquitinating protease USP7 with anticancer activity in vitro | 期刊论文 | Jing Bo;Liu Meng;Yang Li;Cai Hai-yan;Chen Jie-bo;Li Ze-xi;Kou Xi;Wu Yun-zhao;Qin Dong-jun;Zhou Li;Jin Jin;Lei Hu;Xu Han-zhang;Wang Wei-wei;Wu Ying-li |
| 4 | USP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemia | 期刊论文 | Shan Huizhuang;Li Xiangyun;Xiao Xinhua;Dai Yuting;Huang Jinyan;Song Junjun;Liu Meng;Yang Li;Lei Hu;Tong Yin;Zhou Li;Xu Hanzhang;Wu Yingli |
| 5 | Combination of bortezomib and daunorubicin in the induction of apoptosis in T-cell acute lymphoblastic leukemia | 期刊论文 | Du Xin;Tong Jia;Lu Hongying;He Cong;Du Shenghong;Jia Peimin;Zhao Weili;Xu Hanzhang;Li Junmin;Shen Zhixiang;Wu Yingli;Tong Jianhua;Zhou Li |
| 6 | Quinacrine Depletes BCR-ABL and Suppresses Ph-Positive Leukemia Cells | 期刊论文 | Lei Hu;Tu Yaoyao;Yang Li;Jin Jin;Luo Hao;Xu Hanzhang;Kang Jingwu;Zhou Li;Wu Yingli |
| 7 | Overexpression of Fbxo6 inactivates spindle checkpoint by interacting with Mad2 and BubR1. | 期刊论文 | Xu Han-Zhang;Wang Zhuo-Qun;Shan Hui-Zhuang;Zhou Li;Yang Li;Lei Hu;Liu Bin;Wu Ying-Li |
| 8 | Identification of 11(13)-dehydroivaxillin as a potent therapeutic agent against non-Hodgkin's lymphoma | 期刊论文 | Xiao Xinhua;Li Huiliang;Jin Huizi;Jin Jin;Yu Miao;Ma Chunmin;Tong Yin;Zhou Li;Lei Hu;Xu Hanzhang;Zhang Weidong;Liu Wei;Wu Yingli |
| 9 | Vorinostat and quinacrine have synergistic effects in T-cell acute lymphoblastic leukemia through reactive oxygen species increase and mitophagy inhibition. | 期刊论文 | Jing Bo;Jin Jin;Xiang Rufang;Liu Meng;Yang Li;Tong Yin;Xiao Xinhua;Lei Hu;Liu Wei;Xu Hanzhang;Deng Jiong;Zhou Li;Wu Yingli |
查看更多信息请先登录或注册
趋势报告
