卫生毒理学
30925029
2009
H3007.卫生毒理
陈雯
国家杰出青年科学基金
教授
中山大学
200万元
化学致癌；表观遗传；人细胞转化；环境致癌物；生物标志物
2010-01至2013-12
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 化学致癌物诱导人胚肾上皮细胞转化模型的构建 | 期刊论文 | 庞雅琴|陈丽萍|张波|陈雯|李道传|肖勇梅|王庆|赖延东|唐石伏|杨萍| |
| 2 | miR-27a在猿猴病毒小T抗原诱导支气管上皮细胞恶性转化中的作用 | 期刊论文 | 王庆;李道传;刘彩霞;李志芳;肖勇梅;张波;曾晓雯;陈雯 |
| 3 | Upregulation of miR-27a Contributes to the Malignant Transformation of Human Bronchial Epithelial Cells Induced by SV40 Small T Antigen | 期刊论文 | D-C Li|W Chen|Z-F Li|C-X Liu|Y-M Xiao|B Zhang|X-D Li|J Zhao|L-P Chen| |
| 4 | Modulation of DNA Repair Capacity by Ataxia Telangiectasia Mutated Gene Polymorphisms among Polycyclic Aromatic Hydrocarbons-Exposed Workers | 期刊论文 | Wang Yadong;Cheng Juan;Li Daochuan;Duan Huawei;Yang Haijun;Bin Ping;Dai Yufei;Huang Chuanfeng;Liang Xuemiao;Leng Shuguang;Chen Wen;Zheng Yuxin |
| 5 | SV40LT抗原诱导人源性淋巴细胞恶性转化 | 期刊论文 | 彭艳兰;李道传;邢秀梅;魏青;张莹莹;王庆;陈雯;肖勇梅 |
| 6 | 毒作用模式在环境化学物危险度评价中的研究进展 | 期刊论文 | 邢秀梅;张世鑫;陈雯 |
| 7 | Genetic damage induced by organic extract of coke oven emissions on human bronchial epithelial cells | 期刊论文 | Qingfeng Zhai;Huawei Duan;Yadong Wang;Chuanfeng Huang;Yong Niu;Yufei Dai;Ping Bin;Qingjun Liu;Wen Chen;Junxiang Ma;Yuxin Zheng |
| 8 | 毒作用模式在毒理学危险度评价中的研究进展 | 期刊论文 | 张世鑫|邢秀梅|陈雯| |
| 9 | Identification and Functional Analysis of Variant Haplotypes in the 5 '-Flanking Region of Protein Phosphatase 2A-B delta Gene | 期刊论文 | Lin, Yu-Chun|Lin, Li-Na|Chen, Yu-Xi|Wan, Jian-Xin|Luo, Jie|Zhang, Chen-Zi|Li, Xiao-Jie|Hu, Yao-Ming|Mai, Jian-Rong| |
| 10 | 基于毒性通路的毒理学危险度评价方法 | 期刊论文 | 张波;杨萍;陈雯 |
| 11 | Global and MGMT promoter hypomethylation independently associated with genomicinstability of lymphocytes in subjects exposed to high-dose polycyclic aromatichydrocarbon | 期刊论文 | Huawei Duan;Zhini He;Junxiang Ma;Bo Zhang;Zhiguo Sheng;Ping Bin;Juan Cheng;Yong Niu;Haiyan Dong;Han Lin;Yufei Dai;Benzhan Zhu;Wen Chen;Yongmei Xiao;Yuxin Zheng |
| 12 | Aberrant Promoter Methylation of p16 In Peripheral Blood Lymphocytes of Coke-oven Workers and Benzo(a)pyrene-Transformed Human Bronchial Epithelial Cells | 期刊论文 | Ping Yang;Junxiang Ma;Bo Zhang;Huawei Duan;Zhini He;Junling Zeng;Xiaowen Zeng;Daochuan Li;Qing Wang;Yongmei Xiao;Caixia Liu;Qin Xiao;Liping Chen;Xiaonian Zhu;Xiumei Xing;Zhifang Li;Shixin Zhang;Zhengbao Zhang;Lu Ma;Erman Wang;Zhixiong Zhuang;Yuxin Zheng;Wen Chen. |
| 13 | a4 Is Highly Expressed In Carcinogen-transformed Human Cells And Primary Human Cancers | 期刊论文 | Z-X Zhuang|W Chen|D-C Li|X-N Zhu|P Yang|W-X Li|W Zhu|J Zhao|X-D Li| |
| 14 | DNA repair gene deficiency does not predispose human bronchial epithelial cells to benzo(a)pyrene-induced cell transformation | 期刊论文 | Xing Xiumei;Liu Caixia;Tang Shifu;Li Daochuan;Chen Liping;Pang Yaqin;Wang Qing;Zhang Bo;Zeng Xiaowen;Chen Wen;Xiao Yongmei |
| 15 | 转化医学在预防医学领域相关学科中的应用 | 期刊论文 | LIU Cai-xia|刘彩霞|WANG Qing|王庆| |
| 16 | 癌症高发区环境水样有机提取物诱导L-02细胞转化及其表观遗传学机制 | 期刊论文 | 张世鑫;邢秀梅;孙新;何民富;马璐;杨萍;肖勇梅;何志妮;李道传;张波;王庆;陈雯 |
| 17 | Cigarette Smoking and p16 Gene Promoter Hypermethylation in Non-small Cell Lung Carcinoma Patients: a Meta-analysis | 期刊论文 | Bo Zhang;Wei Zhu;Ping Yang;Tao Liu;Mei Jiang;Wei-Qing Chen;Wen Chen |
| 18 | 黄曲霉毒素B1诱导的恶性转化肝细胞miRNA表达谱的变化 | 期刊论文 | WANG Qing|陈雯|LI Dao-chuan|LIU Cai-xia|刘彩霞|LI Zhi-fang|CHEN Wen|李志芳|王庆|LI Wen-xue|李文学|李道传| |
| 19 | DNA损伤修复过程中H2AX磷酸化的调控及其意义 | 期刊论文 | 陈丽萍;朱小年;陈雯 |
| 20 | Aberrant Expression of miR-638 Contributes to Benzo(a)pyrene–induced Human Cell Transformation | 期刊论文 | Yuxin Zheng|Wen Chen|Caixia Liu|Huawei Duan|Xiaowen Zeng|Bo Zhang|Xiaodong Li|Jian Zhao|Shifu Tang| |
| 21 | Loss of PPP2R2A Inhibits Homologous Recombination DNA Repair and Predicts Tumor Sensitivity to PARP Inhibition | 期刊论文 | Kalev P;Simicek M;Vazquez I;Munck S;Chen L;Soin T;Danda N;Chen W;Sablina A. |
| 22 | A novel GSK-3 beta-C/EBP alpha-miR-122-insulin-like growth factor 1 receptor regulatory circuitry in human hepatocellular carcinoma. | 期刊论文 | Zeng, Chunxian|Wang, Ruizhi|Li, Daochuan|Lin, Xue-Jia|Wei, Qing-Kun|Yuan, Yunfei|Wang, Qing|Chen, Wen|Zhuang, Shi-Mei| |
| 23 | 人体细胞转化模型的建立和应用 | 期刊论文 | 陈雯 |
| 24 | Identification and functional analyses of polymorphism haplotypes of protein phosphatase 2A-A alpha gene promoter | 期刊论文 | Lin Yu-Chun;Chen Hui-Feng;Lin Li-Na;Luo Jie;Li Wen;Zhang Shu-Jiang;Li Xiao-Jie;Hu Yao-Ming;Chen Yu-Xi;Chen Wen;Lin Zhong-Ning |
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