CDK7 inhibition suppresses aberrant hedgehog pathway and overcomes resistance to smoothened antagonists

Liu Fang;Jiang Wenyan;Sui Yi;Meng Wei;Hou Linjun;Li Tiantian;Li Meng;Zhang Lei;Mo Jialin;Wang Jiajia;Zhao Yang;Zhang Liye;Ma Jie;Tang Yujie

期刊论文

10.1073/pnas.1815780116

SCIE

Proceedings of the National Academy of Sciences of the United States of America

116#26

2019/6/25

12986#12995

12986#12995

表观遗传元件超级增强子在Hedgehog通路失调肿瘤的发病和治疗中的作用和机制