情感和记忆调控的抑制性神经环路机制

91132303
2011
H0902.意识障碍与认知功能障碍
徐天乐
重大研究计划
教授
上海交通大学
300万元
情感和记忆;紧张性抑制;γ-氨基丁酸受体;甘氨酸受体;抑制性神经环路
2012-01-01到2015-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 2-Guanidine-4-methylquinazoline acts as a novel competitive antagonist of A type g-aminobutyric acid receptors 期刊论文 Xiao X|Zhu MX|Xu TL|
2 2015上海市领军人才 奖励
3 Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction 会议论文 Zhu MX|Zhu MX|Xu TL|Xu TL|
4 Alpha-asarone from Acorus gramineus alleviates epilepsy by modulating A-Type GABA receptors 期刊论文 Wang, Li|Xu, Tian-Le|Wu, Dazheng|Li, Yong|
5 14-3-3 tau Promotes Surface Expression of Cav2.2 (alpha 1B) Ca2+ Channels 期刊论文 Hou, Zhaoyuan|Zhou, Aiwu|Zhou, Yi|Li, Yong|
6 Acid-sensing ion channels: a novel therapeutic target for pain and anxiety 期刊论文 Li WG|Xu TL|
7 GABA Transporter-1 Deficiency Confers Schizophrenia-Like Behavioral Phenotypes 期刊论文 Chen, Zhong|Fei, Jian|Gong, Neng|Xu, Tian-Le|
8 Acid-Sensing Ion Channels: A Novel Therapeutic Target for Pain and Anxiety 期刊论文 Wei-Guang Li|Tian-Le Xu|
9 Role of the potassium chloride cotransporter isoform 2-mediated spinal chloride homeostasisin a rat model of visceral hypersensitivity 期刊论文 Sun J|Li WG|Xu TL|Yuan YZ*|
10 Molecular mechanism of constitutive endocytosis of acid-sensing ion channel 1a and its protective function in acidosis-induced neuronal death 期刊论文 Jiang W|Zhu MX|Li Y|Xu TL|
11 GABA Transporter-1 Deficiency Confers Schizophrenia-Like Behavioral Phenotypes 期刊论文 Chen, Zhong|Fei, Jian|Gong, Neng|Xu, Tian-Le|
12 Highly conserved salt bridge stabilizes rigid signal patch at extracellular loop critical for surface expression of acid-sensing ion channels 期刊论文 Wang J|Zhu MX|Wang R|Xu TL|
13 Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction 会议论文
14 Serotonin facilitates peripheral pain sensitivity in a manner that depends on the nonproton ligand sensing domain of ASIC3 channel 期刊论文 Zeng WZ|Peng Z|Zhu MX|Xu TL|
15 Electrophysiological characterization of methyleugenol: a novel agonist of GABA(A) receptors. 期刊论文 Xu, Tian-Le|Ge, Wei-Hong|Li, Wei-Guang|Li, Fei|
16 Subunit-Specific Inhibition of Glycine Receptors by Curcumol 期刊论文 Michael X. Zhu|Tian-Le Xu|Dazheng Wu|Yong Li|
17 Curcumol from Rhizoma Curcumae suppresses epileptic seizure by facilitation of GABA(A) receptors. 期刊论文 Xu, Tian-Le|Ge, Wei-Hong|Li, Wei-Guang|Li, Fei|
18 Emerging approaches to probing ion channel structure and function 期刊论文 Wei-Guang Li|Tian-Le Xu|
19 Temporal dynamics ofanxiety phenotypes in a dental pulp injury model 期刊论文 Xu TL|Li F|Su J|Li WG|
20 Sequential Posttranslational Modifications Regulate PKC Degradation 期刊论文 Huang C|Zhou A|Zhou Y|Li Y|
21 Intracellular ASIC1a regulates mitochondrial permeability transition-dependent neuronal death. 期刊论文 Tang D|Dong XP|Zhu MX|Xu TL|
22 PI3-kinase/Akt pathway-regulated membrane insertion of acid-sensing ion channel 1a underlies BDNF-induced pain hypersensitivity 期刊论文 Yu H|Zhu MX|Chen ZY|Xu TL|
23 Modulation of GluK2a Subunit-containing Kainate Receptors by 14-3-3 Proteins 期刊论文 Wang Y|Wu Y|Zhou Y|Li Y|
24 Kainate receptor activation induces glycine receptor endocytosis through PKC deSUMOylation 期刊论文 Zhou, Tong|Xu, Tian-Le|Cheng, Jinke|Li, Yong|
25 Targeting acid-sensing ion channels for the treatment of neurological diseases 会议论文
26 Subunit-specificinhibition of glycine receptors by curcumol 期刊论文 Zhu MX|Xu TL|Wu D|Li Y|
27 神经科学研究生创新人才培养的实践和思考 会议论文
28 ASIC3 mediates itch sensation in response to coincident stimulation by acid and nonproton ligand 期刊论文 Wang X|Zhu MX|Cheng XY|Xu TL|
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