细胞命运决定子Numb/Numblike在前列腺细胞对称不对称分裂、谱系分化及肿瘤发生中的作用机制研究
81772743
2017
H1810.肿瘤干细胞
朱鹤
面上项目
研究员
上海交通大学
70万元
细胞分裂模式;肿瘤干细胞;前列腺肿瘤;Numb
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Numb(-/low) Enriches a Castration-Resistant Prostate Cancer Cell Subpopulation Associated with Enhanced Notch and Hedgehog Signaling | 期刊论文 | Guo Yanjing;Zhang Kai;Cheng Chaping;Ji Zhongzhong;Wang Xue;Wang Minglei;Chu Mingliang;Tang Dean G.;Zhu Helen He;Gao Wei-Qiang |
| 2 | E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo | 期刊论文 | Wang Xue;Dong Baijun;Zhang Kai;Ji Zhongzhong;Cheng Chaping;Zhao Huifang;Sheng Yaru;Li Xiaoxia;Fan Liancheng;Xue Wei;Gao Wei-Qiang;Zhu Helen He |
| 3 | Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate | 期刊论文 | Wang Xue;Xu Haibo;Cheng Chaping;Ji Zhongzhong;Zhao Huifang;Sheng Yaru;Li Xiaoxia;Wang Jinming;Shu Yu;He Yuman;Fan Liancheng;Dong Baijun;Xue Wei;Chua Chee Wai;Wu Dongdong;Gao Wei-Qiang;Zhu Helen He |
| 4 | A novel mouse model for liver metastasis of prostate cancer reveals dynamic tumour-immune cell communication. | 期刊论文 | Liu Kaiyuan;Jing Na;Wang Deng;Xu Penghui;Wang Jinming;Chen Xinyu;Cheng Chaping;Xin Zhixiang;He Yuman;Zhao Huifang;Ji ZhongZhong;Zhang Pengcheng;Gao Wei-Qiang;Zhu Helen He;Zhang Kai |
| 5 | Aphthous ulcer drug inhibits prostate tumor metastasis by targeting IKK epsilon/TBK1/NF-kappa B signaling | 期刊论文 | Cheng Chaping;Ji Zhongzhong;Sheng Yaru;Wang Jinming;Sun Yujiao;Zhao Huifang;Li Xiaoxia;Wang Xue;He Yuman;Yao Jufang;Wang Li;Zhang Chenlu;Guo Yanjing;Zhang Jianming;Gao Wei-Qiang;Zhu Helen He |
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