泛素连接酶TRIM59调控胶质瘤发生发展的分子机制
81772663
2017
H1803.肿瘤细胞命运
李彦欣
面上项目
研究员
上海交通大学
55万元
肿瘤转移;TRIM59;胶质瘤;肿瘤发展;EGFR驱动胶质瘤发生
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | PRPS1基因及其突变与相关临床综合征的研究进展 | 期刊论文 | 杨怡;李彦欣 |
| 2 | Targeting PDGFR-activated Glioblastoma through Specific Inhibition of SHP-2-mediated Signaling | 期刊论文 | Youzhou Sang;Yanli Hou;Rongrong Cheng;Liang Zheng;Angel A. Alvarez;Bo Hu;Shi-Yuan Cheng;Weiwei Zhang;Yanxin Li;Haizhong Feng |
| 3 | LncRNA PVT1 regulates triple-negative breast cancer through KLF5/beta-catenin signaling | 期刊论文 | Tang Jianming;Li Yanxin;Sang Youzhou;Yu Bo;Lv Deguan;Zhang Weiwei;Feng Haizhong |
| 4 | Identification of functional cooperative mutations of GNAO1 in human acute lymphoblastic leukemia | 期刊论文 | Lili Song;Bo Yu;Yi Yang;Jianwei Liang;Yingwen Zhang;Lixia Ding;Tianyi Wang;Xinyu Wan;Xiaomin Yang;Jingyan Tang;Shengyue Wang;Benshang Li;Yanxin Li;Haizhong Feng |
| 5 | SHP-2抑制剂在制备靶向前神经元型胶质瘤的药物中的应用 | 专利 | 冯海忠;张伟伟;李彦欣 |
| 6 | Generation of three iPSC lines from different types of pediatric acute leukemia patients | 期刊论文 | Yang Li;Yingwen Zhang;Ting Li;Xiang Wang;Weiqiao Bao;Jun Huang;Yani Ma;Shanshan Li;Siqi wang;Yi Yang;Yanfeng Liu;Yijin Gao;Haizhong Feng;Yanxin Li |
| 7 | PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness | 期刊论文 | 杨怡;宋利利;黄霞;冯亚楠;张莹文;刘延风;李姗姗;战智琰;郑亮;冯海忠;李彦欣 |
| 8 | Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response | 期刊论文 | Yinfang Wang;Yanli Hou;Weiwei Zhang;Angel A. Alvarez;Yongrui Bai;Bo Hu;Shi-Yuan Cheng;Kun Yang;Yanxin Li;Haizhong Feng |
| 9 | TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma | 期刊论文 | Deguan Lv;Yanxin Li;Weiwei Zhang;Angel A. Alvarez;Lina. Song;Jianming Tang;Wei-Qiang Gao;Bo Hu;Shi-Yuan Cheng;Haizhong Feng |
| 10 | The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro | 期刊论文 | Weihua Huang;Haihui Gu;Zhiyan Zhan;Ruoru Wang;Lili Song;Yan Zhang;Yingwen Zhang;Shanshan Li;Jinqi Li;Yan Zang;Yanxin Li;Baohua Qian |
| 11 | iPS细胞技术在HIV研究和治疗中的应用 | 期刊论文 | 战智琰;李彦欣 |
| 12 | Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding | 期刊论文 | Deguan Lv;Feng Jia;Yanli Hou;Youzhou Sang;Angel A. Alvarez;Weiwei Zhang;Wei-Qiang Gao;Bo Hu;Shi-Yuan Cheng;Jianwei Ge;Yanxin Li;Haizhong Feng |
| 13 | KAT6A acetylation of SMAD3 regulates myeloid-derived suppressor cell recruitment, metastasis, and immunotherapy in triple-negative breast cancer | 期刊论文 | Bo Yu;Fei Luo;Bowen Sun;Wenxue Liu;Qiqi Shi;Shi-Yuan Cheng;Ceshi Chen;Guoqiang Chen;Yanxin Li;Haizhong Feng |
| 14 | A novel fusion gene PLEKHA6-NTRK3 in langerhans cell histiocytosis | 期刊论文 | Cai Jiaoyang;Huang Xia;Yin，Minzhi;Pan Ci;Song Lili;Zhan Zhiyan;Chen Jing;Gao Yijin;Tang Jingyan;Li Yanxin;Shen Shuhong |
| 15 | Molecular mechanism of c-Myc and PRPS1/2 against thiopurine resistance in Burkitt's lymphoma | 期刊论文 | Li Ting;Song Lili;Zhang Yingwen;Han Yali;Zhan Zhiyan;Xv Zhou;Li Yang;Tang Yuejia;Yang Yi;Wang Siqi;Li Shanshan;Zheng Liang;Li Yanxin;Gao Yijin |
| 16 | TGF‐β‐activated lncRNA LINC00115 is a critical regulator of glioma stem‐like cell tumorigenicity | 期刊论文 | Jianming Tang;Bo Yu;Yanxin Li;Weiwei Zhang;Angel A Alvarez;Bo Hu;Shi‐Yuan Cheng;Haizhong Feng |
| 17 | CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity | 期刊论文 | Youzhou Sang;Yanxin Li;Yingwen Zhang;Angel A. Alvarez;Bo Yu;Weiwei Zhang;Bo Hu;Shi-Yuan Cheng;Haizhong Feng |
| 18 | Absence of cyclin-dependent kinase inhibitor p27 or p18 increases efficiency of iPSC generation without induction of iPSC genomic instability | 期刊论文 | Zhiyan Zhan;Lili Song;Weiwei Zhang;Haihui Gu;Haizi Cheng;Yingwen Zhang;Yi Yang;Guangzhen Ji;Haizhong Feng;Tao Cheng;Yanxin Li |
| 19 | Modeling leukemia with pediatric acute leukemia patient-derived iPSCs | 期刊论文 | Ting Li;Yingwen Zhang;Yang Li;Xiang Wang;Weiqiao Bao;Jun Huang;Yani Ma;Shanshan Li;Siqi wang;Yi Yang;Yanfeng Liu;Yijin Gao;Haizhong Feng;Yanxin Li |
| 20 | Optimizing the method for generation of integration-free induced pluripotent stem cells from human peripheral blood | 期刊论文 | Gu Haihui;Huang Xia;Xu Jing;Song Lili;Liu Shuping;Zhang Xiao-bing;Yuan Weiping;Li Yanxin |
| 21 | TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3 | 期刊论文 | Sang Youzhou;Li Yanxin;Song Lina;Alvarez Angel A.;Zhang Weiwei;Lv Deguan;Tang Jianming;Liu Feng;Chang Zhijie;Hatakeyama Shigetsugu;Hu Bo;Cheng Shi-Yuan;Feng Haizhong |
| 22 | PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells | 期刊论文 | Jin Wook Kang;Zhiyan Zhan;Guangzhen Ji;Youzhou Sang;Daohong Zhou;Yanxin Li;Haizhong Feng;Tao Cheng |
| 23 | Factors Affecting Mouse Somatic Cell Nuclear Reprogramming by Rabbit Ooplasms | 期刊论文 | Xia Huang;Lili Song;Zhiyan Zhan;Haihui Gu;Haizhong Feng;Yanxin Li |
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