衰老MSC通过MMP1/PAR1信号调控MDS克隆细胞增殖的机制研究

81570108
2015
H0807.骨髓增生异常综合征
常春康
面上项目
主任医师
上海交通大学
55万元
骨髓增生异常综合征;MMP1;骨髓间充质干细胞;骨髓微环境
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Chidamide, a novel histone deacetylase inhibitor, inhibits the viability of MDS and AML cells by suppressing JAK2/STAT3 signaling 期刊论文 Zhao Sida;Guo Juan;Zhao Youshan;Fei Chengming;Zheng Qingqing;Li Xiao;Chang Chunkang
2 骨髓增生异常综合征患者铁代谢参数异常和铁过载状况的研究 期刊论文 宋陆茜;郑晴晴;肖超;郭娟;吴东;苏基滢;周立宇;常春康
3 骨髓间充质干细胞介导恶性血液病耐药的研究进展 期刊论文 费成明;常春康
4 Iron overload promotes erythroid apoptosis through regulating HIF-1a/ROS signaling pathway in patients with myelodysplastic syndrome 期刊论文 Zheng Qing qing;Zhao You shan;Guo Juan;Zhao Si da;Song Lu xi;Fei Cheng ming;Zhang Zheng;Li Xiao;Chang Chun kang
5 Clinical significance of hyaluronan levels and its pro-osteogenic effect on mesenchymal stromal cells in myelodysplastic syndromes 期刊论文 Fei Cheng Ming;Guo Juan;Zhao You Shan;Zhao Si Da;Zhen Qing Qing;Shi Lei;Li Xiao;Chang Chun Kang
6 Downregulation of MMP1 in MDS-derived mesenchymal stromal cells reduces the capacity to restrict MDS cell proliferation 期刊论文 Zhao Sida;Zhao Youshan;Guo Juan;Fei Chengming;Zheng Qingqing;Li Xiao;Chang Chunkang
7 地西他滨治疗骨髓增生异常综合征 及相关肿瘤的疗效预测因素研究 期刊论文 赵佑山;郭娟;许峰;吴东;吴凌云;宋陆茜;肖超;李晓;常春康
8 慢性粒单核细胞白血病的诊断进展 期刊论文 赵思达;赵佑山;常春康;肖志坚
9 Dicer1 downregulation by multiple myeloma cells promotes the senescence and tumor-supporting capacity and decreases the differentiation potential of mesenchymal stem cells 期刊论文 Guo Juan;Zhao Youshan;Fei Chengming;Zhao Sida;Zheng Qingqing;Su Jiying;Wu Dong;Li Xiao;Chang Chunkang
10 胞外囊泡在恶性血液病患者骨髓微环境中作用的研究进展 期刊论文 费成明;常春康
11 Iron overload promotes mitochondrial fragmentation in mesenchymal stromal cells from myelodysplastic syndrome patients through activation of the AMPK/ MFF/Drp1 pathway 期刊论文 Zheng Qingqing;Zhao Youshan;Guo Juan;Zhao Sida;Fei Chengming;Xiao Chao;Wu Dong;Wu Lingyun;Li Xiao;Chang Chunkang
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