β2-AR激动剂福莫特罗调控BCKDC改善恶病质骨骼肌萎缩的作用机制研究

81503155
2015
H3511.临床药理
杨全军
青年科学基金项目
副主任药师
上海交通大学
18万元
支链α酮酸脱氢酶复合物;恶病质;骨骼肌萎缩;临床药理学;福莫特罗
2016-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 司美替尼通过抑制MEK改善肿瘤恶病质骨骼肌萎缩的实验研究 奖励 杨全军;霍炎;韩永龙;万丽丽;李婕;黄金路;卢进;陈朋果;干润;郭澄
2 Abstracts of the 8th International Conference on Cachexia, Sarcopenia and Muscle Wasting, Paris,France, 4-6 December 2015. Integrated analysis of serum and muscle metabonomics reveals metabolic pathway reprogramming during cancer cachexia in a dynamic mouse model 会议论文 Yang Quan-Jun;Yang Gen-Jin;Wan Li-Li;Huo Yan;Yu Qi;Han Yong-Long;Li Bin;Lu Jin;Peng-Guo Chen;Li Jie;Guo Cheng
3 Distinct Metabolic Profile of Inhaled Budesonide and Salbutamol in Asthmatic Children during Acute Exacerbation 期刊论文 Yang Quan-Jun;Zhang Jian-Ping;Zhang Jian-Hua;Han Yong-Long;Xin Bo;Zhang Jing-Xian;Dai Bona;Zhang Yuan;Guo Cheng
4 Protective Effects of Dexrazoxane against Doxorubicin-Induced Cardiotoxicity: A Metabolomic Study. 期刊论文 QuanJun Yang;GenJin Yang;LiLi Wan;YongLong Han;Yan Huo;Jie Li;JinLu Huang;Jin Lu;Run Gan;Cheng Guo
5 Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation 期刊论文 Quan-Jun Yang;Yan Huo;Yong-Long Han;Li-Li Wan;Jie Li;Jin-Lu Huang;Jin Lu;Peng-Guo Chen;Run Gan;Cheng Guo
6 Serum and urine metabolomics study reveals a distinct diagnostic model for cancer cachexia. 期刊论文 Yang Quan-Jun;Zhao Jiang-Rong;Hao Juan;Li Bin;Huo Yan;Han Yong-Long;Wan Li-Li;Li Jie;Huang Jinlu;Lu Jin;Yang Gen-Jin;Guo Cheng
7 Abstracts of the 8th International Conference on Cachexia, Sarcopenia and Muscle Wasting, Paris, France, 4-6 December 2015:β2-AR agonist formoterol triggers the distinct metabolic pathway of leucine in wasting C2C12 myotubes: Application of 13C based stable isotope-resolved metabolomics 会议论文 Quan-Jun Yang;Cheng Guo;Lili Wan;Bin Li;Jinlu Huang;Jie Li;Gen-Jin Yang
8 Nilotinib reverses ABCB1/P-glycoprotein-mediated multidrug resistance but increases cardiotoxicity of doxorubicin in a MDR xenograft model 期刊论文 Zhou Zhi-yong;Wan Li-li;Yang Quan-jun;Han Yong-long;Li Dan;Lu Jin;Guo Cheng
9 Integrated analysis of serum and intact muscle metabonomics identify metabolic profiles of cancer cachexia in a dynamic mouse model 期刊论文 Yang QuanJun;Yang GenJin;Wan LiLi;Huo Yan;Han YongLong;Lu Jin;Li Jie;Huang JinLu;Guo Cheng
10 Abstracts of the 9th International Conference on Cachexia, Sarcopenia and Muscle Wasting, Berlin, Germany, 10–11 December 2016 (part 1). Selumetinib attenuate skeletal muscle wasting in murine cachexia model through ERK inhibition and AKT activation. 会议论文 Yang Quan-Jun;Huo Yan;Han Yong-Long;Wan Li-Li;Li Jie;Huang Jin-Lu;Lu Jin;Guo Cheng
11 一种防治骨骼肌萎缩的治疗药物靶点及其应用 专利 杨全军;郭澄;陈力;陈林林
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