BET和MEK抑制剂协同治疗卵巢癌的研究
81502597
2015
H1814.肿瘤化学药物治疗
景莹
青年科学基金项目
副研究员
上海交通大学
18万元
C24_卵巢肿瘤;MEK抑制剂;细胞凋亡;细胞增殖;BET抑制剂
2016-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Concomitant BET and MAPK blockade for effective treatment of ovarian cancer | 期刊论文 | Jing Ying;Zhang Zhenfeng;Ma Pengfei;An Shimin;Shen Ying;Zhu Liang;Zhuang Guanglei |
| 2 | Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer | 期刊论文 | Ma Pengfei;Fu Yujie;Cai Mei-Chun;Yan Ying;Jing Ying;Zhang Shengzhe;Chen Minjiang;Wu Jie;Shen Ying;Zhu Liang;Chen Hong-Zhuan;Gao Wei-Qiang;Wang Mengzhao;Gu Zhenyu;Bivona Trever G.;Zhao Xiaojing;Zhuang Guanglei |
| 3 | Clonality, Heterogeneity, and Evolution of Synchronous Bilateral Ovarian Cancer | 期刊论文 | Yin Xia;Jing Ying;Cai Mei-Chun;Ma Pengfei;Zhang Yi;Xu Cong;Zhang Meiying;Di Wen;Zhuang Guanglei |
| 4 | Adaptive and Acquired Resistance to EGFR Inhibitors Converge on the MAPK Pathway | 期刊论文 | Ma Pengfei;Fu Yujie;Chen Minjiang;Jing Ying;Wu Jie;Li Ke;Shen Ying;Gao Jian-Xin;Wang Mengzhao;Zhao Xiaojing;Zhuang Guanglei |
| 5 | Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors | 期刊论文 | Zhang Shengzhe;Jing Ying;Ma Pengfei;Di Wen;Zhuang Guanglei;Zhang Shengzhe;Zhang Shengzhe;Zhang Meiying;Yin Xia;Di Wen;Zhuang Guanglei;Zhang Zhenfeng;Wang Xiaojie;Zhuang GL;Zhuang GL |
| 6 | A VEGF-dependent gene signature enriched in mesenchymal ovarian cancer predicts patient prognosis | 期刊论文 | Yin Xia;Wang Xiaojie;Shen Boqiang;Jing Ying;Li Qing;Cai Mei-Chun;Gu Zhuowei;Yang Qi;Zhang Zhenfeng;Liu Jin;Li Hongxia;Di Wen;Zhuang Guanglei |
| 7 | Comprehensive genomic profiling of neuroendocrine bladder cancer pinpoints molecular origin and potential therapeutics | 期刊论文 | Shen Peiye;Jing Ying;Cai Mei-Chun;Ma Pengfei;Zhuang Guanglei;Shen Peiye;Shen Peiye;Chen Haige;Zhuang GL;Chen HG |
| 8 | BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1 | 期刊论文 | Zhang Zhenfeng;Ma Pengfei;Jing Ying;Yan Ying;Cai Mei-Chun;Zhang Meiying;Zhang Shengzhe;Peng Huixin;Ji Zhi-Liang;Di Wen;Gu Zhenyu;Gao Wei-Qiang;Zhuang Guanglei |
| 9 | Preclinical Efficacy and Molecular Mechanism of Targeting CDK7-Dependent Transcriptional Addiction in Ovarian Cancer | 期刊论文 | Zhang Zhenfeng;Peng Huixin;Wang Xiaojie;Yin Xia;Ma Pengfei;Jing Ying;Cai Mei-Chun;Liu Jin;Zhang Meiying;Zhang Shengzhe;Shi Kaixuan;Gao Wei-Qiang;Di Wen;Zhuang Guanglei |
| 10 | Prevalence and clonality of synchronous primary carcinomas in the bladder and prostate | 期刊论文 | Jing Ying;Zhang Ruiyun;Ma Pengfei;Cai Mei-Chun;Zhuang Guanglei;Chen Haige |
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