胰岛素经SREBP1/HDGF蛋白质复合体重编程脂代谢诱发肝癌的机制和意义
81572719
2015
H1807.肿瘤代谢
赵小平
面上项目
研究员
上海交通大学
55万元
脂质新生;蛋白间相互作用;C09_肝和肝内胆管肿瘤;固醇调节元件结合蛋白;代谢重编程
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Pyruvate kinase M2 interacts with nuclear sterol regulatory element-binding protein 1a and thereby activates lipogenesis and cell proliferation in hepatocellular carcinoma | 期刊论文 | Zhao Xiaoping;Zhao Li;Yang Hao;Li Jiajin;Min Xuejie;Yang Fajun;Liu Jianjun;Huang Gang |
| 2 | Role of transgelin-2 in diabetes-associated pancreatic ductal adenocarcinoma | 期刊论文 | Sun Yan;He Weiwei;Luo Man;Zhou Yuhong;Chang Guilin;Ren Weiying;Wu Kefen;Li Xi;Shen Jiping;Zhao Xiaoping;Hu Yu |
| 3 | PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma | 期刊论文 | Yang H.;Zhao X.;Zhao L.;Liu L.;Li J.;Jia W.;Liu J.;Huang G. |
| 4 | Phosphorylation of Ser6 in hnRNPA1 by S6K2 regulates glucose metabolism and cell growth in colorectal cancer. | 期刊论文 | Sun Yan;Luo Man;Chang Guilin;Ren Weiying;Wu Kefen;Li Xi;Shen Jiping;Zhao Xiaoping;Hu Yu |
| 5 | ACLY facilitates colon cancer cell metastasis by CTNNB1 | 期刊论文 | Wen Jun;Min Xuejie;Shen Mengqin;Hua Qian;Han Yuan;Zhao Li;Liu Liu;Huang Gang;Liu Jianjun;Zhao Xiaoping |
| 6 | Inhibition of SREBP increases gefitinib sensitivity in non-small cell lung cancer cells. | 期刊论文 | Li Jiajin;Yan Hui;Zhao Li;Jia Wenzhi;Yang Hao;Liu Liu;Zhou Xiang;Miao Ping;Sun Xiaoguang;Song Shaoli;Zhao Xiaoping;Liu Jianjun;Huang Gang |
| 7 | Non-canonical roles of PFKFB3 in regulation of cell cycle through binding to CDK4 | 期刊论文 | Jia W;Zhao X;Zhao L;Yan H;Li J;Yang H;Huang G;Liu J |
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趋势报告
