肺癌抑制基因GPRC5A对STAT3信号通路的调控作用研究
81572693
2015
H1802.肿瘤发生
姚烽
面上项目
副主任医师
上海交通大学
57万元
STAT3;肺肿瘤;动物模型;IL-6;C05_气管;支气管;GPRC5A
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | ALDH2 Repression Promotes Lung Tumor Progression via Accumulated Acetaldehyde and DNA Damage | 期刊论文 | Li K;Guo W;Li Z;Wang Y;Sun B;Xu D;Ling J;Song H;Liao Y;Wang T;Jing B;Hu M;Kuang Y;Wang Q;Yao F;Sun A;Zhu L;Wang L;Deng J |
| 2 | Dysregulated ENPP1 increases the malignancy of human lung cancer by inducing epithelial-mesenchymal transition phenotypes and stem cell features | 期刊论文 | Min Hu;Wenzheng Guo;Yueling Liao;Dongliang Xu;Beibei Sun;Hongyong Song;Tong Wang;Yanbin Kuang;Bo Jing;Kaimi Li;Jing Ling;Feng Yao;Jiong Deng |
| 3 | Gprc5a-deficiency confers susceptibility to endotoxin-induced acute lung injury via NF-kB pathway | 期刊论文 | Yueling Liao;Hongyong Song;Dongliang Xu;Huike Jiao;Feng Yao;Jingyi Liu;Yadi Wu;Shuangshuang Zhong;Huijing Yin;Shuli Liu;Xiaofei Wang;Wenzheng Guo;Beibei Sun;Baohui Han;Y. Eugene Chin;Jiong Deng |
| 4 | IL6/STAT3 Signaling Q2 Orchestrates Premetastatic Niche 4 Q3 Formation and Immunosuppressive Traits in Lung | 期刊论文 | Jing B;Wang T;Sun B;Xu J;Xu D;Liao Y;Song H;Guo W;Li K;Hu M;Zhang S;Ling J;Kuang Y;Zhang T;Zhou BP;Yao F;Deng J |
| 5 | Stabilization of PTGES by deubiquitinase USP9X promotes metastatic features of lung cancer via PGE(2) signaling | 期刊论文 | Wang Tong;Jing Bo;Sun Beibei;Liao Yueling;Song Hongyong;Xu Dongliang;Guo Wenzheng;Li Kaimi;Hu Min;Liu Shuli;Ling Jing;Kuang Yanbin;Feng Yao;Zhou Binhua P;Deng Jiong |
| 6 | Gprc5a-knockout mouse lung epithelial cells predicts ceruloplasmin, lipocalin 2 and periostin as potential biomarkers at early stages of lung tumorigenesis | 期刊论文 | Sun Beibei;Guo Wenzheng;Hu Song;Yao Feng;Yu Keke;Xing Jie;Wang Ronghua;Song Hongyong;Liao Yueling;Wang Tong;Jiang Pengfei;Han Baohui;Deng Jiong |
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