前蛋白转换酶Furin在破骨细胞骨吸收中的分子机制研究
81572167
2015
H0608.骨、关节、软组织退行性病变
秦安
面上项目
研究员
上海交通大学
51万元
前蛋白转化酶Furin;破骨细胞;骨质疏松症
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | TGF-beta synergizes with ML264 to block IL-1 beta-induced matrix degradation mediated by Kruppel-like factor 5 in the nucleus pulposus | 期刊论文 | Xie Ziang;Jie Zhiwei;Wang Gangliang;Sun Xuewu;Tang Pan;Chen Shuai;Qin An;Wang Jian;Fan Shunwu |
| 2 | A Novel Diterpenoid Suppresses Osteoclastogenesis and Promotes Osteogenesis by Inhibiting Ifrd1-Mediated and IB-Mediated p65 Nuclear Translocation | 期刊论文 | Xie Zi'ang;Yu Hejun;Sun Xuewu;Tang Pan;Jie Zhiwei;Chen Shuai;Wang Jiying;Qin An;Fan Shunwu |
| 3 | Vx-11e protects against titanium-particle-induced osteolysis and osteoclastogenesis by supressing ERK activity | 期刊论文 | Li Chen;Wu Zuoxing;Yuan Guixin;Fang Zhanfei;Lin Xixi;Pu Ruoyu;Kang Yanbin;Li Li;Shao Siyuan;Ding Jiaxin;Zhao Jinmin;Liu Qian;Qin An |
| 4 | Nirogacestat suppresses RANKL-Induced osteoclast formation in vitro and attenuates LPS-Induced bone resorption in vivo | 期刊论文 | Chen Xuzhuo;Chen Xinwei;Zhou Zhihang;Mao Yi;Wang Yexin;Ma Zhigui;Xu Weifeng;Qin An;Zhang Shanyong |
| 5 | SREBP-2 aggravates breast cancer associated osteolysis by promoting osteoclastogenesis and breast cancer metastasis | 期刊论文 | Jie Zhiwei;Xie Ziang;Xu Wenbin;Zhao Xiangde;Jin Gu;Sun Xuewu;Huang Bao;Tang Pan;Wang Gangliang;Shen Shuying;Qin An;Fan Shunwu |
| 6 | Biodegradable and biocompatible high elastic chitosan scaffold is cell-friendly both in vitro and in vivo | 期刊论文 | Pang Yichuan;Qin An;Lin Xianfeng;Yang Lin;Wang Qiang;Wang Zhengke;Shan Zhi;Li Shengyun;Wang Jiying;Fan Shunwu;Hu Qiaoling |
| 7 | Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network | 期刊论文 | Gao Junjie;Qin An;Liu Delin;Ruan Rui;Wang Qiyang;Yuan Jun;Cheng Tak Sum;Filipovska Aleksandra;Papadimitriou J M;Dai Kerong;Jiang Qing;Gao Xiang;Feng Jian Q;Takayanagi Hiroshi;Zhang Changqing;Zheng Ming H |
| 8 | Autologous fibroblasts induce fibrosis of the nucleus pulposus to maintain the stability of degenerative intervertebral discs. | 期刊论文 | Chen Chen;Tangjun Zhou;Xiaojiang Sun;Chen Han;Kai Zhang;Changqing Zhao;Xunlin Li;Haijun Tian;Xiao Yang;Yifan Zhou;Zhiqian Chen;An Qin;Jie Zhao |
| 9 | Bone-targeted methotrexate-alendronate conjugate inhibits osteoclastogenesis in vitro and prevents bone loss and inflammation of collagen-induced arthritis in vivo | 期刊论文 | Xie Zi'ang;Liu Guanxiong;Tang Pan;Sun Xuewu;Chen Shuai;Qin An;Zhu Peizhi;Zhang Jianfeng;Fan Shunwu |
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