软骨干细胞分化调控及复合温敏性原位成型水凝胶修复关节软骨

81572123
2015
H0604.骨、关节、软组织损伤与修复
张晓玲
面上项目
研究员
上海交通大学
60万元
原位成型;软骨修复;分化调控;水凝胶;软骨干细胞
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Sophoridine from Sophora Flower Attenuates Ovariectomy Induced Osteoporosis through the RANKL-ERK-NFAT Pathway. 期刊论文 Zhao X;Mei L;Pei J;Liu Z;Shao Y;Tao Y;Zhang X;Jiang L
2 Sitagliptin, an anti-diabetic drug, suppresses estrogen deficiency-induced osteoporosis in vivo and inhibits RANKL-induced osteoclast formation and bone resorption in vitro. 期刊论文 Wang C;Xiao F;Qu X;Zhai Z;Hu G;Chen X;Zhang X
3 Nardosinone suppresses RANKL-induced osteoclastogenesis and attenuates lipopolysaccharide- induced alveolar bone resorption. 期刊论文 Niu C;Xiao F;Yuan K;Hu X;Lin W;Ma R;Zhang X;Huang Z
4 IL-12p40 impairs mesenchymal stem cell-mediated bone regeneration via CD4+ T cells. 期刊论文 Xu J;Wang Y;Li J;Zhang X;Geng Y;Huang Y;Dai K;Zhang X
5 TNF-α inhibits SATB2 expression and osteoblast differentiation through NK-kB and MAPK pathways. 期刊论文 Zuo C;Zhao X;Shi Y;Wu W;Zhang N;Xu J;Wang C;Hu G;Zhang X
6 Interleukin-17A-promoted MSC2 polarization related with new bone formation of ankylosing spondylitis. 期刊论文 He T;Huang Y;Zhang C;Liu D;Cheng C;Xu W;Zhang X
7 High-dose TGF-β1 impairs mesenchymal stem cell-mediated bone regeneration via Bmp2 inhibition. 期刊论文 Xu J;Liu J;Gan Y;Dai K;Zhao J;Huang M;Huang Y;Zhuang Y;Zhang X
8 Meta-analysis of urinary C-terminal telopeptide of type II collagen as a biomarker in osteoarthritis diagnosis. 期刊论文 Huang M;Zhao J;Huang Y;Dai L;Zhang X
9 Overexpression of mechanical sensitive miR-337-3p alleviates ectopic ossification in rat tendinopathy model via targeting IRS1 and Nox4 of tendon derived stem cells. 期刊论文 Geng Y;Zhao X;Xu J;Zhang X;Hu G;Fu SC;Dai K;Chen X;Patrick YS;Zhang X
10 Regulation of immune response by bioactive ions released from silicate bioceramics for bone regeneration. 期刊论文 Huang Y;Wu C;Zhang X;Chang J;Dai K
11 miR-146a interacting with lncRNA EPB41L4A-AS1 and lncRNA SNHG7 inhibits proliferation of bone marrow-derived mesenchymal stem cells. 期刊论文 Cui P;Zhao X;Liu J;Chen X;Gao Y;Tao K;Wang C;Zhang X
12 PIP5k1β controls bone homeostasis through modulating both osteoclast and osteoblast differentiation. 期刊论文 Zhao X;Cui P;Hu G;Wang C;Jiang L;Zhao J;Xu J;Zhang X
13 miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2. 期刊论文 Zhang X;Wang C;Zhao J;Xu J;Geng Y;Dai L;Huang Y;Fu S;Dai K;Zhang X
14 MiR-144 Inhibits Tumor Growth and Metastasis in Osteosarcoma via Dual-suppressing RhoA/ROCK1 Signaling Pathway. 期刊论文 Liu JL;Li J;Xu JJ;Xiao F;Cui PL;Qiao ZG;Chen XD;Tao WD;Zhang XL
15 Osteon Myospalacem Baileyi attenuates osteoclast differentiation trough RANKL induced NFAT pathways. 期刊论文 Cui Y;Zhao X;Mei L;Pei J;Wang S;Shao Y;Tao Y;Zhang X;Jiang L
16 MiR-146a deletion protects from bone loss in OVX mice by suppressing RANKL/OPG and M-CSF in bone microenvironment. 期刊论文 Zhao J;Huang M;Zhang X;Xu J;Hu G;Zhao X;Cui P;Zhang X
17 Anti-inflammatory and anti-osteoarthritis effects of tectorigenin. 期刊论文 Wang CL;Li D;Wang CD;Xiao F;Zhu JF;Shen C;Zuo B;Cui YM;Wang H;Gao Y;Hu GL;Zhang XL;Chen XD
18 BMPER Enhances Bone Formation by Promoting the Osteogenesis-Angiogenesis Coupling Process in Mesenchymal Stem Cells. 期刊论文 Xiao F;Wang C;Wang C;Gao Y;Zhang X;Chen X
19 Improving Bone Regeneration Using Chordin siRNA Delivered by pH-Responsive and Non-Toxic Polyspermine Imidazole-4,5-Imine. 期刊论文 Wang C;Xiao F;Gan Y;Yuan W;Zhai Z;Jin T;Chen X;Zhang X
20 Modification and evaluation of micro-nano structured porous bacterial cellulose scaffold for bone tissue engineering. 期刊论文 Huang Y;Wang J;Yang F;Shao Y;Zhang X;Dai K
21 Mechanical stimulation orchestrates the osteogenic differentiation of human bone marrow stromal cells by regulating HDAC1. 期刊论文 Wang J;Wang CD;Zhang N;Tong WX;Zhang YF;Shan SZ;Zhang XL;Li QF
22 MicroRNA-145 attenuates TNF-α-driven cartilage matrix degradation in osteoarthritis via direct suppression of MKK4 期刊论文 Hu G;Zhao X;Wang C;Geng Y;Zhao J;Xu J;Zuo B;Zhao C;Wang C;Zhang X
23 TNF-α-induced LRG1 promotes angiogenesis and mesenchymal stem cell migration in the subchondral bone during osteoarthritis. 期刊论文 Wang Y;Xu J;Zhang X;Wang C;Huang Y;Dai K;Zhang X
24 一种成骨检测试剂盒及促进骨修复的植入物 专利 张晓玲;徐佳佳
25 miR-337-3p过表达方案在预防治疗肌腱病及韧带骨化或钙化病中的应用 专利 张晓玲;耿倚云
26 miR-146a及其靶点在治疗骨关节炎中的应用 专利 张晓玲;张旭东
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