TLR9介导的STAT3通路缺陷导致HIES患儿记忆性B细胞发育障碍的分子机制的研究

81571605
2015
H1108.免疫缺陷性疾病
陈同辛
面上项目
主任医师
上海交通大学
58万元
STAT3通路缺陷;Toll样受体9;高IgE综合征;记忆性B细胞
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Degradation Products of Polydopamine Restrained Inflammatory Response of LPS-Stimulated Macrophages Through Mediation TLR-4-MYD88 Dependent Signaling Pathways by Antioxidant 期刊论文 Jin Liang;Yuan Feng;Chen Chenxin;Wu Jing;Gong Ruolan;Yuan Guangyin;Zeng Hui;Pei Jia;Chen Tongxin
2 Decreased PD-1 expression on circulating CD4( )T cell and PD-Ll expression on myeloid dendritic cell correlate with clinical manifestations in systemic juvenile idiopathic arthritis 期刊论文 Cai Li;Zhang Chenxing;Wu Jing;Zhou Wei;Chen Tongxin
3 When WAS Gene Diagnosis Is Needed: Seeking Clues Through Comparison Between Patients With Wiskott-Aldrich Syndrome and Idiopathic Thrombocytopenic Purpura 期刊论文 Jin Ying Ying;Wu Jing;Chen Tong Xin;Chen Ji
4 DNA induction of MDM2 promotes proliferation of human renal mesangial cells and alters peripheral B cells subsets in pediatric systemic lupus erythematosus 期刊论文 Chenxing Zhang;Ji Chen;Li Cai;Jing Wu;Jiayuan Wang;Lanfang Cao;Wei Zhou;Tongxin Chen
5 Systemic Vasculitis and High IgE Level in a Patient with LPS-Responsive Beige-Like Anchor (LRBA) Deficiency 期刊论文 Wu Jing;Wang Wei Fan;Chen Tong Xin;Chen Ji
6 Clinical Manifestations and Genetic Analysis of 17 Patients with Autosomal Dominant Hyper-IgE Syndrome in Mainland China: New Reports and a Literature Review 期刊论文 JingWu;Chen Ji;Tian Zhi Qing;Zhang Hao;Gong Ruo Lan;Chen Tong Xin;Hong Li
7 In vitro study of the inflammatory cells response to biodegradable Mg-based alloy extract 期刊论文 Jin Liang;Wu Jing;Yuan Guangyin;Chen Tongxin
8 Clinical characteristics and genetic profiles of 174 patients with X-linked agammaglobulinemia Report from Shanghai, China (2000-2015) 期刊论文 Chen Xia-Fang;Wang Wei-Fan;Zhang Yi-Dan;Zhao Wei;Wu Jing;Chen Tong-Xin
9 Clinical Manifestation of Hyper IgE Syndrome Including Otitis Media 期刊论文 Wu Jing;Hong Li;Chen Tong Xin
10 A Biodegradable Mg-Based Alloy Inhibited the Inflammatory Response of THP-1 Cell-Derived Macrophages Through the TRPM7–PI3K–AKT1 Signaling Axis 期刊论文 Jiang Jin;Chenxin Chen;Yutong Li;Ruolan Gong;Jing Wu;Hua Zhang;Bin Kang;Guan-Yin Yuan;Hui Zeng;Tong-Xin Chen
11 Immunoregulatory effect of human beta-defensin 1 on neonatal cord blood monocyte-derived dendritic cells and T cells 期刊论文 Wu Jing;Gong Ruo Lan;Hu Qing Feng;Chen Xu Ting;Zhao Wei;Chen Tong Xin
12 原发性免疫缺陷病的分子机制及精准诊疗研究 奖励 陈同辛;金莹莹;吴静;陈夏芳;王琳琳;曹睿明
13 Clinical Features and Genetic Analysis of 48 Patients with Chronic Granulomatous Disease in a Single Center Study from Shanghai, China (2005-2015): New Studies and a Literature Review 期刊论文 Wu Jing;Wang Wei Fan;Zhang Yi Dan;Chen Tong Xin
14 A Novel Mutation of Notch homolog protein 2 gene in a Chinese Family with Hajdu-Cheney Syndrome 期刊论文 Gong Ruo-Lan;Wu Jing;Chen Tong-Xin
15 常染色体显性遗传高IgE综合征患儿外周血循环B淋巴细胞亚群表型分析 期刊论文 田志青;陈戟;吴静;张浩;洪莉;陈同辛
16 Serum IP-10 is useful for identifying renal and overall disease activity in pediatric systemic lupus erythematosus 期刊论文 Zhang Chen xing;Cai Li;Shao Kang;Wu Jing;Zhou Wei;Cao Lan fang;Chen Tong xin
17 TLR7、TLR9激动剂对人外周血B细胞作用的研究 期刊论文 龚若兰;吴静;陈同辛
18 Clinical, Laboratory, and Molecular Characteristics and Remission Status in Children With Severe Congenital and Non-congenital Neutropenia 期刊论文 Gong Ruo Lan;Wu Jing;Chen Tong Xin
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