miR-200c通过MYCN调控MDS细胞恶性生物学特征的分子机制及靶向干预研究

81470291
2014
H0807.骨髓增生异常综合征
李晓
面上项目
教授
上海交通大学
70万元
MDS;miR-200c;发病机制;MYCN;骨髓增生异常综合征/;表观遗传学
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Rigosertib as a selective anti-tumor agent can ameliorate multiple dysregulated signaling transduction pathways in high-grade myelodysplastic syndrome 期刊论文 Xu Feng;He Qi;Li Xiao;Chang Chun-Kang;Wu Ling-Yun;Zhang Zheng;Liu Li;Shi Wen-Hui;Zhu Yang;Zhao You-Shan;Gu Shu-Cheng;Fei Cheng-Ming;Guo Juan;Wu Dong;Zhou Liyu;Li X
2 Genomic loss of EZH2 leads to epigenetic modifications and overexpression of the HOX gene clusters in myelodysplastic syndrome 期刊论文 Xu Feng;Liu Li;Chang Chun-Kang;He Qi;Wu Ling-Yun;Zhang Zheng;Shi Wen-Hui;Guo Juan;Zhu Yang;Zhao You-Shan;Gu Shu-Cheng;Fei Cheng-Ming;Li Xiao;Li X
3 Whole-exome and targeted sequencing identify ROBO1 and ROBO2 mutations as progression-related drivers in myelodysplastic syndromes 期刊论文 李晓
4 Exploration of the role of gene mutations in myelodysplastic syndromes through a sequencing design involving a small number of target genes 期刊论文 Xu Feng;Wu Ling-Yun;He Qi;Wu Dong;Zhang Zheng;Song Lu-Xi;Zhao You-Shan;Su Ying;Zhou Li-Yu;Guo Juan;Chang Chun-Kang;Li Xiao;Chang CK;Li X
5 Identification of microRNA-regulated pathways using an integration of microRNA-mRNA microarray and bioinformatics analysis in CD34+cells of myelodysplastic syndromes 期刊论文 Xu Feng;Zhu Yang;He Qi;Wu Ling-Yun;Zhang Zheng;Shi Wen-Hui;Liu Li;Chang Chun-Kang;Li Xiao;Li X
6 MYCN contributes to the malignant characteristics of erythroleukemia through EZH2-mediated epigenetic repression of p21 期刊论文 Liu Li;Xu Feng;Chang Chun-Kang;He Qi;Wu Ling-Yun;Zhang Zheng;Li Xiao;Li X
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