三种睾丸特异性丝氨酸蛋白酶家族成员的生理功能、在男性不育症发病中的作用及其分子机制研究
81430028
2014
H0405.精子发生异常与男性不育
王铸钢
重点项目
教授
上海交通大学
320万元
精子受精能力;男性不育症;基因剔除小鼠模型;丝氨酸蛋白酶家族;精卵识别/结合
2015-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Establishment, characterization, and application of pAcr-SP-NTP-EGFP transgenic mice in visualizing the oviduct-migrating ability of sperm from Prss37- mice. | 期刊论文 | Shen Chunling();Wang Jinjin;Zhuang Hua;Liu Jianbing;Wang Xiyi;Chen Xuejiao;Wu Zhuanbin;Wu Wenting;Wu Youbing;Sun Yanwen;Yan Huimin;Fei Jian;Kuang Ying();Wang Zhugang() |
| 2 | 长链非编码RNA与雄性生殖 | 期刊论文 | 李朝杰;沈春玲;王铸钢 |
| 3 | Lacking of palladin leads to multiple cellular events changes which contribute to NTD | 期刊论文 | Tan Juan;Chen Xue Jiao;Shen Chun Ling;Zhang Hong Xin;Tang Ling Yun;Lu Shun Yuan;Wu Wen Ting;Kuang Ying;Fei Jian;Wang Zhu Gang |
| 4 | Nhe5 deficiency enhances learning and memory via upregulating Bdnf/TrkB signaling in mice | 期刊论文 | Chen Xuejiao;Wang Xiyi;Tang Lingyun;Wang Jinjin;Shen Chunling;Liu Jianbing;Lu Shunyuan;Zhang Hongxin;Kuang Ying;Fei Jian;Wang Zhugang |
| 5 | Serine protease PRSS55 is crucial for male mouse fertility via affecting sperm migration and sperm-egg binding. | 期刊论文 | Shang Xuan;Shen Chunling;Liu Jianbing;Tang Lingyun;Zhang Hongxin;Wang Yicheng;Wu Wenting;Chi Jun;Zhuang Hua;Fei Jian;Wang Zhugang |
| 6 | Two novel testis-specific long noncoding RNAs produced by 1700121C10Rik are dispensable for male fertility in mice | 期刊论文 | Chaojie Li;Chunling Shen;Xuan Shang;Lingyun Tang;Wenfeng Xiong;Haoyang Ge;Hongxin Zhang;Shunyuan Lu;Yan Shen;Jinjin Wang;Jian Fei;Zhugang Wang |
| 7 | Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and Cyp2e1 expression levels. | 期刊论文 | Cui Xiaofang;Ma Benting;Wang Yan;Chen Yan;Shen Chunling;Kuang Ying;Fei Jian;Lu Lungen;Wang Zhugang |
| 8 | Ablation of Tacr2 in mice leads to gastric emptying disturbance | 期刊论文 | Mao Y L;Shen C L;Zhou T;Ma B T;Tang L Y;Wu W T;Zhang H X;Lu H L;Xu W X;Wang Z G |
| 9 | An update of the regulatory factors of sperm migration from the uterus into the oviduct by genetically manipulated mice | 期刊论文 | Wenfeng Xiong;Zhugang Wang;Chunling Shen |
| 10 | DHTKD1 Deficiency Causes Charcot-Marie-Tooth Disease in Mice. | 期刊论文 | Xu Wang-Yang;Zhu Houbao;Shen Yan;Wan Ying-Han;Tu Xiao-Die;Wu Wen-Ting;Tang Lingyun;Zhang Hong-Xin;Lu Shun-Yuan;Jin Xiao-Long;Fei Jian;Wang Zhu-Gang |
| 11 | A point mutation in Fgf9 impedes joint interzone formation leading to multiple synostoses syndrome | 期刊论文 | Tang Lingyun;Wu Xiaolin;Zhang Hongxin;Lu Shunyuan;Wu Min;Shen Chunling;Chen Xuejiao;Wang Yicheng;Wang Weigang;Shen Yan;Gu Mingmin;Ding Xiaoyi;Jin Xiaolong;Fei Jian;Wang Zhugang |
| 12 | Gpr110 deficiency decelerates carcinogen-induced hepatocarcinogenesis via activation of the IL-6/STAT3 pathway | 期刊论文 | Ma Benting;Zhu Junjie;Tan Juan;Mao Yulei;Tang Lingyun;Shen Chunling;Zhang Hongxing;Kuang Ying;Fei Jian;Yang Xiao;Wang Zhugang |
| 13 | 丝氨酸蛋白酶与生殖 | 期刊论文 | 尚璇;沈春玲;王铸钢 |
| 14 | Low levels of PRSS37 protein in sperm are associated with many cases of unexplained male infertility. | 期刊论文 | Liu Jianbing;Shen Chunling;Fan Weimin;Chen Yan;Zhang Aijun;Feng Yun;Li Zheng;Kuang Ying;Wang Zhugang |
| 15 | Tafa-2 plays an essential role in neuronal survival and neurobiological function in mice. | 期刊论文 | Wang Xiyi;Shen Chunling;Chen Xuejiao;Wang Jinjin;Cui Xiaofang;Wang Yicheng;Zhang Hongxin;Tang Lingyun;Lu Shunyuan;Fei Jian;Wang Zhugang |
| 16 | Palladin is involved in platelet activation and arterial thrombosis. | 期刊论文 | Chen Xuejiao;Fan Xuemei;Tan Juan;Shi Panlai;Wang Xiyi;Wang Jinjin;Kuang Ying;Fei Jian;Liu Junling;Dang Suying;Wang Zhugang |
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