rhIL-1Ra防治肿瘤化疗所致中性粒细胞减少症的药理机制研究

81173113
2011
H3509.血液、泌尿与生殖系统药物药理
韩伟
面上项目
教授
上海交通大学
60万元
CIN;CRC;IL-1Ra;Pharmacology
2012-01-01到2015-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 rhIL-1ra蛋白质的HPLC法测定 期刊论文 张如亮|贾世香|屠平|韩伟|
2 Recombinant human interleukin-1 receptor antagonist (rhIL-1Ra) attenuates caerulein-induced chronic pancreatitis in mice 期刊论文 Wu, Mingyuan|Yu, Yan|Han, Wei|Wang, Xingpeng|
3 IL-1Ra selectively protects intestinal cryptepithelial cells, but not tumor cells, from chemotoxicity via p53-mediatedupregulation of p21WAF1 and p27KIP1 期刊论文 Wang X,Zhu SY,Qian L,*Yu Y,*Han W|
4 Generation and Characterization of a NewMonoclonal Antibody Against CXCL4 期刊论文 Wu Mingyuan|Gao Jin, Wang Xia, Zhang Yang, Zhu Shunying|Yu Yan|Han Wei|
5 rhIL-1Ra预防肿瘤化疗多器官损伤新药研究 奖励
6 Development of a cell-based qualitative assayfor detection of neutralizing anti-human interleukin-1 receptor antagonist (hIL-1Ra)antibodies in rats 期刊论文 Jin Gao|Jingjing Li, Minmin Yang, Mingyuan Wu, Ping Tu|Yan Yu|Wei Han|
7 Exogenous IL-1Ra attenuates intestinal mucositisinduced by oxaliplatin and 5-fluorouracil through suppression of p53-dependentapoptosis 期刊论文 Gao J|Qian L, Gao J, Zhu S, Wu M, Zhang Y, Guan W|Yu Y|Han W|
8 Recombinant human interleukin-1 receptorantagonist reduces acute lethal toxicity and protects hematopoiesis fromchemotoxicity in vivo 期刊论文 Qian L, Xiang D, Zhang J, Yu Y,*Han W, *Wu MY|
9 Recombinant human interleukin-1 receptor antagonist reduces acute lethal toxicity and protects hematopoiesis from chemotoxicity in vivo 期刊论文 Shen, Jiaqing|Yu, Yan|Han, Wei|Wu, Mingyuan|
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