Atm 介导的Smad1 磷酸化在DNA损伤应激反应及肿瘤发生中的作用

81130039
2011
H18.肿瘤学
李保界
重点项目
教授
上海交通大学
280万元
Smad1;肿瘤;Atm;磷酸化修饰;DNA损伤
2012-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Identification of Bisindolylmaleimide IX as a potential agent to treat drug-resistant BCR-ABL positive leukemia 期刊论文 Ruan, Xinsen|Jia, Hao|Wang, Xueying|Li, Baojie|
2 c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16(INK4a) expression 期刊论文 Chen, Guo-Qiang|He, Lin|Goff, Stephen P.|Li, Baojie|
3 Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy 期刊论文 Thibault, Helene|Scherrer-Crosbie, Marielle|Goff, Stephen P.|Li, Baojie|
4 p53 Regulates Neural Stem Cell Proliferation and Differentiation via BMP-Smad1 Signaling and Id1 期刊论文 Liu, Feng|Li, Jing|He, Lin|Li, Baojie|
5 The dynamic behavior of Ect2 in response to DNA damage 期刊论文 He, Dan|Xiang, Jinnan|Li, Baojie|Liu, Huijuan|
6 Identification of 5-Iodotubercidin as a Genotoxic Drug with Anti-Cancer Potential 期刊论文 Deng, Yuezhen|Xie, Dong|He, Lin|Li, Baojie|
7 Mesenchymal stem cell aging: Mechanisms and influences on skeletal and non-skeletal tissues 期刊论文 Liu, Huijuan|Xia, Xuechun|Li, Baojie|
8 Smad1 stabilization and delocalization in response to the blockade of BMP activity 期刊论文 Liu, Huijuan|Li, Baojie|Hao, Aijun|Li, Jing|
9 p57Kip2 is an unrecognized DNA damage response effector molecule that functions in tumor suppression and chemoresistance 期刊论文 Ao, J.|Zuo, Q.|Fu, C.|Li, B.|
10 A role for c-Abl in cell senescence and spontaneous immortalization 期刊论文 He, Lin|Wang, Xueying|Wan, Yue|Li, Baojie|
11 A potential role for protein palmitoylation and zDHHC16 in DNA damage response 期刊论文 Li, Baojie|Zhao, Peiquan|Zeng, Li|Li, Jing|
12 p53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers 期刊论文 Liu, Huijuan|Habib, Samy L.|Fu, Chuangang|Li, Baojie|
13 A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response 期刊论文 He, Lin|Wang, Xueying|Yu, Qiang|Li, Baojie|
14 An Unconventional Role of BMP-Smad1 Signaling in DNA Damage Response: A Mechanism for Tumor Suppression 期刊论文 Bao, Dandan|Xia, Xuechun|Chau, Jenny Fung Ling|Li, Baojie|
15 p38 alpha MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions 期刊论文 Zhang, Zhen-Lin|Jiang, Xinquan|Liu, Huijuan|Li, Baojie|
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