RNA-自噬siRNA自组装纳米材料的构建及其调控肺血管重构的机制
81429001
2014
H0105.慢性阻塞性肺疾病
毛诚德
海外及港澳学者合作研究基金
教授
中国人民解放军第三军医大学
200万元
RNA；自噬基因Atg101；；自组装纳米材料；；肺血管重构；信号通路p53/Gli
2015-01至2018-12
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Regulation on Toll-like Receptor 4 and Cell Barrier Function by Rab26 siRNA-loaded DNA Nanovector in Pulmonary Microvascular Endothelial Cells | 期刊论文 | Hongli Li();Binfeng He();Xueping Liu;Jingtong Li;Qian Liu;Weijie Dong;Zhi Xu;Guisheng Qian;Hua Zuo;Changhua Hu;Hang Qian;Chengde Mao();Guansong Wang() |
| 2 | De novo design of an RNA tile that self-assembles into a homo-octameric nanoprism | 期刊论文 | Yu, Jinwen; Liu, Zhiyu; Jiang, Wen; Wang, Guansong; Mao, Chengde |
| 3 | ATG101 Single-Stranded Antisense RNA-Loaded Triangular DNA Nanoparticles Control Human Pulmonary Endothelial Growth via Regulation of Cell Macroautophagy | 期刊论文 | Du, Juan; Xu, Zhi; Liu, Qian; Yang, Yu; Qian, Hang; Hu, Mingdong; Fan, Ye; Li, Qi; Yao, Wei; Li, Hongli; Qian, Guisheng; He, Binfeng; Zhou, Deshan; Mao, Chengde; Wang, Guansong |
| 4 | Isothermal Self-Assembly of Spermidine-DNA Nanostructure Complex as a Functional Platform for Cancer Therapy | 期刊论文 | Wang Dong;Liu Qian;Wu Di;He Binfeng;Li Jin;Mao Chengde;Wang Guansong;Qian Hang |
| 5 | In vivo production of RNA nanostructures via programmed folding of single-stranded RNAs | 期刊论文 | Li, Mo; Zheng, Mengxi; Wu, Siyu; Tian, Cheng; Liu, Di; Weizmann, Yossi; Jiang, Wen; Wang, Guansong; Mao, Chengde |
| 6 | Retrosynthetic Analysis-Guided Breaking Tile Symmetry for the Assembly of Complex DNA Nanostructures | 期刊论文 | Pengfei Wang;Siyu Wu;Cheng Tian;Guimei Yu;Wen Jiang;Guansong Wang;Chengde Mao |
| 7 | 一种三角板形核酸纳米制剂及制备方法和应用 | 专利 | 王关嵩;王应明;尤再春;杨俊俊 |
| 8 | Self-assembled triangular DNA nanoparticles are an efficient system for gene delivery | 期刊论文 | Yingming Wang();Zaichun You();Juan Du();Hongli Li;Huaping Chen;Jingtong Li;Weijie Dong;Binfeng He;Chengde Mao();Guansong Wang() |
| 9 | Regulation of vascular smooth muscle cell autophagy by DNA nanotube-conjugated mTOR siRNA | 期刊论文 | You Zaichun;Qian Hang;Wang Changzheng;He Binfeng;Yan Jiawei;Mao Chengde;Wang Guansong |
| 10 | Capturing intracellular oncogenic microRNAs with self-assembled DNA nanostructures for microRNAbased cancer therapy | 期刊论文 | Liu, Qian; Wang, Dong; Yuan, Ming; He, Binfeng; Li, Jin; Mao, Chengde; Wang, Guansong; Qian, Hang |
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