基于斑马鱼平台结合多种模型系统研究三七花皂苷促血管新生作用及机制

81328025
2013
H3209.中药心脑血管药理
李铭源
海外及港澳学者合作研究基金
教授
上海中医药大学
20万元
三七花;血管新生;斑马鱼;大鼠心梗模型;机制研究
2014-01至2015-12
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 血管新生与冠心病治疗性血管生成 期刊论文 张少言;林赟霄;陈浩;王佑华
2 Pro-angiogenic activity of notoginsenoside R1 in human umbilical vein endothelial cells in vitro and in a chemical-induced blood vessel loss model of zebrafish in vivo. 期刊论文 Yang BR;Hong SJ;Lee SM;Cong WH;Wan JB;Zhang ZR;Zhang QW;Zhang Y;Wang YT;Lin ZX
3 Discovery of a benzofuran derivative (MBPTA) as a novel ROCK inhibitor that protects against MPP(+)-induced oxidative stress and cell death in SH-SY5Y cells. 期刊论文 Chong CM;Shen M;Zhou ZY;Pan P;Hoi PM;Li S;Liang W;Ai N;Zhang LQ;Li CW;Yu H;Hou T;Lee SM
4 VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation. 期刊论文 Li S;Dang YY;Che GO;Kwan YW;Chan SW;Leung GP;Lee SM;Hoi MP
5 Study on the HPLC chromatograms and pro-angiogenesis activities of the flowers of Panax notoginseng 期刊论文 Rui-Fang Xie;Bin-Rui Yang;Pei-Pei Cheng;Shen Wu;Zhi-Cheng Li;Jing-Yi Tang;Shang Li;Nuo Tang;Simon Ming Yuen Lee;You-Hua Wang;Xin Zhou
6 阿奇霉素对斑马鱼心脏毒性的初步研究. 期刊论文 崔国祯;周鹤峰;陈焕娴;李铭源
7 Transcriptome analysis of leaves, roots and flowers of Panax notoginseng identifies genes involved in ginsenoside and alkaloid biosynthesis. 期刊论文 Liu MH;Yang BR;Cheung XF;Yang KY;Zhou HF;Kwok JSL;Liu GC;Li XF;Zhong SL;Lee SMY;Tsui SKW
8 Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway 期刊论文 Li Shang;Dang Yuan Ye;Zhou Xue Lin;Huang Bin;Huang Xiao Hui;Zhang Zhe Rui;Kwan Yiu Wa;Chan Shun Wan;Leung George Pak Heng;Lee Simon Ming Yuen;Hoi Maggie Pui Man
9 Basal Flt1 tyrosine kinase activity is a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis. 期刊论文 Li S;Zhou XL;Dang YY;Kwan YW;Chan SW;Leung GP;Lee SM;Hoi MP
10 In vivo Angiogenesis Screening and Mechanism of Action of Novel Tanshinone Derivatives Produced by One-pot Combinatorial Modification of Natural Tanshinone Mixture from Salvia Miltiorrhiza. 期刊论文 Zhang ZR;Li JH;Li S;Liu AL;Hoi PM;Tian HY;Ye WC;Lee SM;Jiang RW
11 Amelioration of acute myocardial infarction by saponins from flower buds of Panax notoginseng via pro-angiogenesis and anti-apoptosis. 期刊论文 Yang BR;Cheung KK;Zhou X;Xie RF;Cheng PP;Wu S;Zhou ZY;Tang JY;Hoi PM;Wang YH;Lee SM
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