风湿病和临床免疫
81325019
2013
H1107.自身免疫性疾病
张烜
国家杰出青年科学基金
教授
中国医学科学院北京协和医院
200万元
系统性红斑狼疮;发病机制;诊断;治疗;
2014-01至2017-12
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Symptomatic knee osteonecrosis in patients with systemic lupus erythematosus: a case-control study | 期刊论文 | Zhao Lidan;Wu Xiuhua;Wu Honghua;Su Jinmei;Zhang Wen;Zhao Yan;Zhang Xuan;Zheng Wenjie |
| 2 | CXCR4异常表达调控在SLE发病机制中的作用 | 会议论文 | 吴湘妮;赵丽丹;许潇天;尹玉峰;梁迪;唐福林;李永哲;张烜 |
| 3 | Anti-cyclic citrullinated Peptide antibody is associated with interstitial lung disease in patients with rheumatoid arthritis. | 期刊论文 | Yin Yufeng;Liang Di;Zhao Lidan;Li Yang;Liu Wei;Ren Yan;Li Yongzhe;Zeng Xiaofeng;Zhang Fengchun;Tang Fulin;Shan Guangliang;Zhang Xuan |
| 4 | Evaluation of synovial angiogenesis in patients with rheumatoid arthritis using (6)(8)Ga-PRGD2 PET/CT: a prospective proof-of-concept cohort study. | 期刊论文 | Zhu, Zhaohui; Yin, Yufeng; Zheng, Kun; Li, Fang; Chen, Xiaoyuan; Zhang, Fengchun; Zhang, Xuan（共同通讯作者，排位1） |
| 5 | Contribution and underlying mechanisms of CXCR4 overexpression in patients with systemic lupus erythematosus | 期刊论文 | Zhao Li-dan();Liang Di;Wu Xiang-ni;Li Yang;Niu Jing-wen;Zhou Chen;Wang Li;Chen Hua;Zheng Wen-jie;Fei Yun-yun;Tang Fu-lin;Li Yong-zhe;Zhang Feng-chun;He Wei;Cao Xue-tao;Zhang Xuan |
| 6 | Hyperactivation and in situ recruitment of inflammatory V delta 2 T cells contributes to disease pathogenesis in systemic lupus erythematosus | 期刊论文 | Mao Yujia;Yin Shanshan;Li Xuemei;Yue Cai;Zhou Chen;Huang Linfang;Mo Wenxiu;Liang Di;Zhang Jianmin;He Wei;Zhang Xuan |
| 7 | Hyperactivation and in situ recruitment of inflammatory Vdelta2 T cells contributes to disease pathogenesis in systemic lupus erythematosus. | 期刊论文 | Yin, Shanshan; Mao, Yujia; Li, Xuemei; Yue, Cai; Zhou, Chen; Huang, Linfang; Mo, Wenxiu; Liang, Di; Zhang, Jianmin; He, Wei; Zhang, Xuan（共同通讯作者，排位1） |
| 8 | Impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice | 期刊论文 | Yin Yufeng;Zhao Lidan;Zhang Fengchun;Zhang Xuan |
| 9 | Chemotaxis of Vδ2 T cells to the joints contributes to the pathogenesis of rheumatoid arthritis | 期刊论文 | zhang xuan |
| 10 | B cells biology in systemic lupus erythematosus-from bench to bedside. | 期刊论文 | Zhao LiDan;Ye YanXia;Zhang Xuan |
| 11 | The TRIFRA trial: efforts employed to minimise expectation bias | 期刊论文 | Lv Qian-wen;Zhang Wen;Shi Qun;Zheng Wen-jie;Lipsky Peter E.;Zhang Xuan |
| 12 | Systemic Autoimmune Diseases 2014 | 期刊论文 | Shi, Guixiu; Zhang, Jianying; Zhang, Zhixin Jason; Zhang, Xuan |
| 13 | Response to DM Marcus's comment on the TRIFRA study (comparison of Tripterygium wilfordii Hook F vs methotrexate in the treatment of active rheumatoid arthritis) | 期刊论文 | Lv, Qian-wen; Zhang, Wen; Shi, Qun; Zheng, Wen-jie; Lipsky, Peter E.; Zhang, Xuan（共同通讯作者，排位1） |
| 14 | 原发性胆汁性肝硬化发病机制、临床诊断与治疗的研究 | 奖励 | 张奉春();李永哲;王立;费允云;胡朝军;张烜;张文;邓垂文;张蜀澜;李萍;彭琳一;赵岩;曾小峰;唐福林;董怡 |
| 15 | 原发性干燥综合征发病机制及临床多器官损伤的研究 | 奖励 | 张奉春();李永哲;吕力为;张文;张烜;陈华;费允云;林响;吴子燕;李娅;杨云娇;赵岩;曾小峰;唐福林;董怡 |
| 16 | TwHF versus methotrexate in the treatment of rheumatoid arthritis: response to Landewe's comment on the TRIFRA study | 期刊论文 | Lv, Qian-wen; Chen, Tao; Zhang, Wen; Shi, Qun; Zheng, Wen-jie; Lipsky, Peter E.; Zhang, Xuan（共同通讯作者，排位1） |
| 17 | Defective PTEN regulation contributes to B cell hyperresponsiveness in systemic lupus erythematosus. | 期刊论文 | Wu Xiang-ni;Ye Yan-xia;Niu Jing-wen;Li Yang;Li Xin;You Xin;Chen Hua;Zhao Li-dan;Zeng Xiao-feng;Zhang Feng-chun;Tang Fu-lin;He Wei;Cao Xue-tao;Zhang Xuan;Lipsky Peter E |
| 18 | Comparison of Tripterygium wilfordii Hook F with methotrexate in the treatment of active rheumatoid arthritis (TRIFRA): a randomised, controlled clinical trial. | 期刊论文 | Lv, QianWen; Zhang, Wen; Shi, Qun; Zheng, Wenjie; Li, Xin; Chen, Hua; Wu, Qingjun; Jiang, Wanlan; Li, Hongbin; Gong, Lu; Wei, Wei; Liu, Hui; Liu, Aijing; Jin, Hongtao; Wang, Junxiang; Liu, Xiu-mei; Li, Zhen-bin; Liu, Bin; Shen, Min; Wang, Qian; Wu, Xiangni; Liang, Di; Yin, Yufeng; Fei, Yunyun; Su, Jingmei; Zhao, Lidan; Jiang, Ying; Li, Jing; Tang, Fulin; Zhang, Fengchun; Lipsky, Peter E; Zhang, Xuan（共同通讯作者，排位1） |
| 19 | Effect of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor on disease activity in patients with rheumatoid arthritis: a meta-analysis. | 期刊论文 | Tang, Fulin|Zhang, Fengchun|Shan, Guangliang|Zhang, Xuan| |
| 20 | The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment. | 期刊论文 | Zhang Xuan;Zhang Dongya;Jia Huijue;Feng Qiang;Wang Donghui;Liang Di;Wu Xiangni;Li Junhua;Tang Longqing;Li Yin;Lan Zhou;Chen Bing;Li Yanli;Zhong Huanzi;Xie Hailiang;Jie Zhuye;Chen Weineng;Tang Shanmei;Xu Xiaoqiang;Wang Xiaokai;Cai Xianghang;Liu Sheng;Xia Yan;Li Jiyang;Qiao Xingye;Al-Aama Jumana Yousuf;Chen Hua;Wang Li... |
| 21 | 类风湿关节炎患者外周血Vδ2T细胞向滑膜组织趋化研究 | 会议论文 | 殷珊珊;周晨;何维;张烜 |
| 22 | miR-7表达抑制剂在制备治疗系统性红斑狼疮药物中的应用 | 专利 | 李扬 |
| 23 | PTEN调节缺陷导致系统性红斑狼疮患者B细胞的高反应性 | 会议论文 | 吴湘妮;叶燕霞;牛婧雯;李扬;李芯;尤欣;陈华;赵丽丹;曾小峰;张奉春;唐福林;何维;曹雪涛;张烜;peter E.Lipsky |
| 24 | Integration of microbiome and epigenome to decipher the pathogenesis of autoimmune diseases | 期刊论文 | 张烜 |
| 25 | 一种ACPA阴性的RA诊断标志物及其应用 | 专利 | 张烜;莫文秀;李永哲;胡朝军;刘国振;武丽君 |
| 26 | Osteoimmunology: memorandum for rheumatologists | 期刊论文 | Zhao L; Huang L; Zhang X |
| 27 | Aberrant CD200/CD200R1 expression and its potential role in Th17 cell differentiation, chemotaxis and osteoclastogenesis in rheumatoid arthritis. | 期刊论文 | Zhang, Fengchun|He, Wei|Cao, Xuetao|Zhang, Xuan| |
| 28 | The status of rheumatoid factor and anti-cyclic citrullinated peptide antibody are not associated with the effect of anti-TNFalpha agent treatment in patients with rheumatoid arthritis: a meta-analysis. | 期刊论文 | Qianwen Lv;Yufeng Yin;Xin Li;Guangliang Shan;Xiangni Wu;Di Liang;Yongzhe Li;Xuan Zhang |
| 29 | Bone Marrow Megakaryocytes May Predict Therapeutic Response of Severe Thrombocytopenia in Patients with Systemic Lupus Erythematosus | 期刊论文 | Zhao Lidan;Xu Dong;Qiao Lin;Zhang Xuan |
| 30 | 一个预测RA药物疗效的诊断标志物及其应用 | 专利 | 张烜; 莫文秀 |
| 31 | Pregnancy-Related Systemic Lupus Erythematosus: Clinical Features, Outcome and Risk Factors of Disease Flares - A Case Control Study | 期刊论文 | Yang Huaxia;Liu Hui;Xu Dong;Zhao Lidan;Wang Qian;Leng Xiaomei;Zheng Wenjie;Zhang Fengchun;Tang Fulin;Zhang Xuan |
| 32 | CD200在制备系统性红斑狼疮治疗药物中的应用 | 专利 | 张烜 |
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趋势报告
