肿瘤分子生物学
81225016
2012
H18.肿瘤学
雷群英
国家杰出青年科学基金
教授
复旦大学
200万元
肿瘤代谢;乙酰化;抑癌基因;TAZ;M2型丙酮酸激酶
2013-01至2016-12
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Oxidative stress activates SIRT2 to deacetylate and stimulate phosphoglycerate mutase. | 期刊论文 | Deng, Chu-Xia|Guan, Kun-Liang|Lei, Qun-Ying|Xiong, Yue| |
| 2 | PARD3 induces TAZ activation and cell growth by promoting LATS1 and PP1 interaction | 期刊论文 | Lv Xian-Bo; Liu Chen-Ying; Wang Zhen; Sun Yi-Ping; Xiong Yue; Lei Qun-Ying; Guan Kun-Liang |
| 3 | Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. | 期刊论文 | Gao Xue();Lin Shu-Hai;Ren Feng;Li Jin-Tao;Chen Jia-Jia;Yao Chuan-Bo;Yang Hong-Bin;Jiang Shu-Xia;Yan Guo-Quan;Wang Di;Wang Yi;Liu Ying;Cai Zongwei;Xu Ying-Ying;Chen Jing;Yu Wenqiang;Yang Peng-Yuan();Lei Qun-Ying() |
| 4 | Estrogen regulates Hipposignaling via GPER in breast cancer. | 期刊论文 | Zhou X; Wang S; Wang Z; Feng X; Liu P; Lv XB; Li F; Yu FX; Sun Y; Yuan H; Zhu H; Xiong Y; Lei QY; Guan KL |
| 5 | NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells | 期刊论文 | Di Zhao; Yan Mo; Meng-Tian Li; Shao-Wu Zou; Zhou-Li Cheng; Yi-Ping Sun; Yue Xiong; Kun-Liang Guan; Qun-Ying Lei |
| 6 | Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization. | 期刊论文 | Lei Lv;Yan-Ping Xu;Di Zhao;Fu-Long Li;Wei Wang;Naoya Sasaki;Ying Jiang;Xin Zhou;Ting-Ting Li;Kun-Liang Guan;Qun-Ying Lei;Yue Xiong |
| 7 | Lysine -5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer | 期刊论文 | Di Zhao();Shao-Wu Zou();Ying Liu;Xin Zhou;Yan Mo;Ping Wang;Yan-Hui Xu;Bo Dong;Xiong Yue();Qun-Ying Lei();Kun-Liang Guan() |
| 8 | Acetylation of MAT IIalpha represses tumour cell growth and is decreased in human hepatocellular cancer. | 期刊论文 | Yang Hong-Bin();Xu Ying-Ying()();Zhao Xiang-Ning;Zou Shao-Wu();Zhang Ye;Zhang Min;Li Jin-Tao;Ren Feng;Wang Li-Ying;Lei Qun-Ying() |
| 9 | Glyceraldehyde-3-phosphate dehydrogenase is activated by lysine 254 acetylation in response to glucose signal. | 期刊论文 | Li Tingting; Liu Mengxi; Feng Xu; Wang Zhen; Das Indrani; Xu Yanping; Zhou Xin; Sun Yiping; Guan Kun-Liang; Xiong Yue; Lei Qun-Ying |
| 10 | Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth | 期刊论文 | Ruiting, Lin|Ren, Tao|Xue, Gao|Tingting, Li|Xin, Zhou|Kun-Liang, Guan|Yue, Xiong|Lei, Qun-Ying| |
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