正常皮肤和皮肤疾病的分子机制研究

81225013
2012
H1202.皮肤免疫性疾病
陈翔
国家杰出青年科学基金
教授
中南大学
200万元
CD147;皮肤肿瘤;银屑病;正常皮肤
2013-01至2016-12
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity. 期刊论文 Zhang Jianglin;Lei Zhou;Huang Zunnan;Zhang Xu;Zhou Youyou;Luo Zhongling;Zeng Weiqi;Su Juan;Peng Cong;Chen Xiang
2 CD147 Interacts with NDUFS6 in Regulating Mitochondrial Complex I Activity and the Mitochondrial Apoptotic Pathway in Human Malignant Melanoma Cells. 期刊论文 Kuang, Y|Chen, M|Su, J|Chen, X|
3 Cyclin-dependent kinase 2 (CDK2) is a key mediator for EGF-induced cell transformation mediated through the ELK4/c-Fos signaling pathway 期刊论文 Peng cong;Zeng weiqi;Su Juan;Kuangyehong;He yijin;Zhao shuang;Zhang jiangling;Ma weiya;Bode AM;Dong zigang(共同通讯作者);Chen Xiang(共同通讯作者)
4 CD147 promotes melanoma progression through hypoxia-induced MMP2 activation. 期刊论文 Zeng W;Su J;Wu L;Yang D;Long T;Li D;Kuang Y;Li J;Qi M;Zhang J;Chen X
5 A novel interaction between calcium-modulating cyclophilin ligand and Basigin regulates calcium signaling and matrix metalloproteinase activities in human melanoma cells. 期刊论文 Qi, Min|Zeng, Weiqi|Zhang, Jianglin|Chen, Xiang|
6 TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin 期刊论文 Luo zhongling;Zhang xu;Zeng weiqi;Su juan;Yang keda;Lu lixia;Lim chuanbian;Tang wen;Wu lisha;Zhao Shuang;Jia xuekun;Peng cong(共同通讯作者);Chen xiang(共同通讯作者)
7 Overexpression of HMGB1 in melanoma predicts patient survival and suppression of HMGB1 induces cell cycle arrest and senescence in association with p21 (Waf1/Cip1) up-regulation via a p53-independent, Sp1-dependent pathway. 期刊论文 Jiang, Minghao|Liu, Zhaoqian|Zhou, Honghao|Chen, Xiang|
8 DNAJB1 stabilizes MDM2 and contributes to cancer cell proliferation in a p53-dependent manner. 期刊论文 Qi, Min|Zhang, Jianglin|Zeng, Weiqi|Chen, Xiang|
9 High Expression of SOX2 and OCT4 Indicates Radiation Resistance and an Independent Negative Prognosis in Cervical Squamous Cell Carcinoma 期刊论文 Shen Liangfang();Huang Xinqiong;Xie Xiaoxue;Su Juan;Yuan Jun;Chen Xiang()
10 TNFR1 Regulates Ovarian Cancer Cell Tumorigenicity Through PIK3CB-p110Beta 期刊论文 Peng cong;Su juan;Zeng weiqi;Zhang xu;Chen xiang
11 CD147 silencing inhibits tumor growth by suppressing glucose transport in melanoma. 期刊论文 Zeng, Weiqi|Zhao, Shuang|Peng, Cong|Chen, Xiang|
12 alphaNAC inhibition of the FADD-JNK axis plays anti-apoptotic role in multiple cancer cells. 期刊论文 Peng, C|Su, J|Chen, X|Yuan, Z|
13 Tivozanib reverses multidrug resistance mediated by ABCB1 (P-glycoprotein) and ABCG2 (BCRP) 期刊论文 Yang D.;Kathawala R. J.;Chufan E. E.;Patel A.;Ambudkar S. V.;Chen Z. S.;Chen X.
14 CD147 mediates chemoresistance in breast cancer via ABCG2 by affecting its cellular localization and dimerization 期刊论文 Zhou Shuangyuan;Liao Liqiu;Chen Chen;Zeng Weiqi;Liu Shuang;Su Juan;Zhao Shuang;Chen Mingliang;Kuang Yehong;Chen Xiang;Li Jie
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