高分子基因载体

51222307
2012
E0308.生物医用有机高分子材料
田华雨
优秀青年科学基金项目
研究员
中国科学院长春应用化学研究所
100万元
高分子基因载体;基因治疗;抗肿瘤;遮蔽体系;靶向性
2013-01至2015-12
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Thermo-/pH-dual responsive properties of hyperbranched polyethylenimine grafted by phenylalanine 期刊论文 Chen Jie;Xia Jialiang;Tian Huayu;Tang Zhaohui;He Chaoliang;Chen Xuesi
2 Codelivery of Antitumor Drug and Gene by a pH-Sensitive Charge-Conversion System 期刊论文 Guan Xiuwen;Li Yanhui();Jiao Zixue;Lin Lin;Chen Jie;Guo Zhaopei;Tian Huayu();Chen Xuesi
3 Multi-armed poly(aspartate-g-OEI) copolymers as versatile carriers of pDNA/siRNA 期刊论文 Dong Xuan;Lin Lin;Chen Jie;Tian Huayu;Xiao Chunsheng;Guo Zhaopei;Li Yuce;Wei Yen;Chen Xuesi
4 miRNA oligonucleotide and sponge for miRNA-21 inhibition mediated by PEI-PLL in breast cancer therapy 期刊论文 Gao Shiqian; Tian Huayu; Guo Ye; Li Yuce; Guo Zhaopei; Zhu Xiaojuan; Chen Xuesi
5 A pH-sensitive charge-conversion system for doxorubicin delivery 期刊论文 Guan Xiuwen;Li Yanhui;Jiao Zixue;Chen Jie;Guo Zhaopei;Tian Huayu();Chen Xuesi
6 Cationic Dendron-Bearing Lipids: Investigating Structure-Activity Relationships for Small Interfering RNA Delivery 期刊论文 Zhang Yu;Chen Jie;Xiao Chunsheng;Li Mingqiang;Tian Huayu;Chen Xuesi()
7 Pulmonary Codelivery of Doxorubicin and siRNA by pH-Sensitive Nanoparticles for Therapy of Metastatic Lung Cancer 期刊论文 Xu Caina;Wang Ping;Zhang Jingpeng;Tian Huayu();Park Kinam;Chen Xuesi()
8 Polymeric Gene Carriers for Anti-tumor Treatment 会议论文 Tian Huayu;Chen Xuesi
9 Synergistic treatment of cancer stem cells by combinations of antioncogenes and doxorubicin 期刊论文 Jie Chen();Lin Lin;Zhaopei Guo;Caina Xu;Huayu Tian();Kinam Park;Xuesi Chen
10 Effective tumor treatment by VEGF siRNA complexed with hydrophobic poly(amino acid)-modified polyethylenimine 期刊论文 Chen Jie;Tian Huayu;Dong Xuan;Guo Zhaopei;Jiao Zixue;Li Feifan;Kano Arihiro;Maruyama Atsushi;Chen Xuesi
11 Pulmonary co-delivery system forlung tumor treatment 会议论文 Tian Huayu;Xu Caina;Wang Ping;Chen Xuesi
12 pH-sensitive OEI-poly(aspartic acid-b-lysine) as charge shielding system for gene delivery 会议论文 Feng Tianshi;Tian Huayu;Dong Xuan;Lam Michael Hon-Wah;Liang Haojun;Chen Xuesi
13 Hyaluronic acid based injectable hydrogels for localized and sustained gene delivery 会议论文 Li Yuce;Tian Huayu;Chen Xuesi
14 Polylysine-modified polyethylenimine inducing tumor apoptosis as an efficient gene carrier 期刊论文 Tian Huayu;Lin Lin;Jiao Zixue;Guo Zhaopei;Chen Jie;Gao Shiqian;Zhu Xiaojuan;Chen Xuesi
15 Hydrophobic polyalanine modified hyperbranched polyethylenimine as high efficient pDNA and siRNA carrier 期刊论文 Guo Zhaopei;Tian Huayu;Lin Lin;Chen Jie;He Chaoliang;Tang Zhaohui;Chen Xuesi
16 Doxorubicin-loaded PLGA microparticles with internal pores for long-acting release in pulmonary tumor inhalation treatment 期刊论文 Feng Tianshi;Tian Huayu();Xu Caina;Lin Lin;Lam Michael HonWah;Liang Haojun;Chen Xuesi
17 聚氨基酸改性高分子基因载体 会议论文 田华雨;郭兆培;林琳;陈杰;焦自学;关秀文;王萍;陈学思
18 Application of zwitterionic polymers in the treatment of malignant tumors 期刊论文 Chen Jie;Li Xiaozhou;Tian Huayu();Zhu Xiaojuan;Chen Xuesi
19 Gold Nanoparticles for Cancer Theranostics 期刊论文 Liang Hong; Tian Huayu; Deng Mingxiao; Chen Xuesi
20 Pulmonary delivery systems for metastatic metastatic treatment 会议论文 Tian Huayu;Feng Tianshi;Xu Caina;Wang Ping;Chen Xuesi
21 PEGylated poly(aspartate-g-OEI) copolymers for effective and prolonged gene transfection 期刊论文 Feng Tianshi;Dong Xuan;Tian Huayu();Lam Michael Hon-Wah;Liang Haojun;Wei Yen;Chen Xuesi
22 Hydrophobic poly (amino acid)-modified PEI-mediated delivery of single-chain antibody scFv1C9 inhibits HepG2 cell cycle process and xenograft growth in nude mice 期刊论文 Fu Chunling;Zheng Daxue;Shi Hengliang;Tian Huayu;Zhu Xiaojuan;Chen Xuesi
23 Polylysine-modified polyethylenimines as siRNA carriers for effective tumor treatment 期刊论文 Chen Jie();Jiao Zi-xue;Lin Lin;Guo Zhao-pei;Xu Cai-na;Li Yan-hui;Tian Hua-yu();Chen Xue-si
24 Efficient recovery of precious metal based on Au-S bond and electrostatic interaction 期刊论文 Li Yuce;Tian Huayu;Xiao Chunsheng;Ding Jianxun;Chen Xuesi
25 聚乙烯亚胺介导siRNA和顺铂协同抗肿瘤治疗 期刊论文 焦自学;陈杰;田华雨;陈学思
26 PLK1shRNA and doxorubicin co-loaded thermosensitive PLGA-PEG-PLGA hydrogels for osteosarcoma treatment 期刊论文 Hecheng Ma;Chaoliang He;Yilong Cheng;Dongsong Li;Yubao Gong;Jianguo Liu;Huayu Tian;Xuesi Chen
27 Synergistic co-delivery of doxorubicin and paclitaxel by porous PLGA microspheres for pulmonary inhalation treatment 期刊论文 Tianshi Feng;Huayu Tian;Caina Xu;Lin Lin;Zhigang Xie;Michael Hon-Wah Lam;Haojun Liang;Xuesi Chen
28 Pulmonary Drugs and Genes Delivery Systems for Lung Disease Treatment 期刊论文 Xu Caina;Tian Huayu;Chen Xuesi
29 A Serum-Tolerant Hydroxyl-Modified Polyethylenimine as Versatile Carriers of pDNA/siRNA 期刊论文 Dong Xuan;Lin Lin;Chen Jie;Guo Zhaopei;Tian Huayu;Li Yuce;Wei Yen;Chen Xuesi
30 Charge-conversional zwitterionic copolymer as pH-sensitive shielding system for effective tumor treatment 期刊论文 Jie Chen();Xuan Dong;Tianshi Feng;Lin Lin;Zhaopei Guo;Jialiang Xia;Huayu Tian();Xuesi Chen()
31 Guanidinated Thiourea-Decorated Polyethylenimines for Enhanced Membrane Penetration and Efficient siRNA Delivery 期刊论文 Li Yuce;Tian Huayu();Ding Jianxun;Lin Lin;Chen Jie;Gao Shiqian;Chen Xuesi()
32 Polyethylenimines modified by amino acids with different charge states and hydrophilic/hydrophobic properties for gene carriers 会议论文 Ying Zhang;Huayu Tian;Xiuwen Guan;Huapan Fang;Nan Yan;Xuesi Chen
33 Thiourea modified polyethylenimine for efficient gene delivery mediated by the combination of electrostatic interactions and hydrogen bonds 期刊论文 Li Yuce;Tian Huayu;Ding Jianxun;Dong Xuan;Chen Jie;Chen Xuesi()
34 Nanoparticles for Gene Delivery 期刊论文 Tian Huayu;Chen Jie;Chen Xuesi()
35 A pH sensitive co-delivery system of siRNA and doxorubicin for pulmonary administration to B16F10 metastatic lung cancer 期刊论文 Xu Caina();Tian Huayu();Sun Hai;Jiao Zixue;Zhang Ying;Chen Xuesi
36 pH-responsive zwitterionic copolypeptides as charge conversional shielding system for gene carriers 期刊论文 Tian Huayu;Guo Zhaopei;Lin Lin;Jiao Zixue;Chen Jie;Gao Shiqian;Zhu Xiaojuan();Chen Xuesi()
37 pH敏感的基因载体遮蔽体系 会议论文 田华雨;关秀文;陈学思
38 高分子基因载体在胶质瘤治疗中的应用 会议论文 田华雨;高世乾;Yousra Saeed Malik;Muhammad Abid Sheikh;陈学思
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