冠状病毒基因组复制的分子机制

30925003
2009
C0107.病毒学
郭德银
国家杰出青年科学基金
教授
武汉大学
200万元
SARS冠状病毒；RNA基因组；亚基因组；复制酶；RNA加工酶
2010-01至2013-12
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Hepatitis C Virus Sensitizes Host Cells to TRAIL-Induced Apoptosis by Up-Regulating DR4 and DR5 via a MEK1-Dependent Pathway 期刊论文 Deng, Zhongfan|Yan, Huijuan|Hu, Jiajie|Zhang, Shengwei|Peng, Peng|Liu, Qingzhen|Guo, Deyin|
2 SARS-CoV nucleocapsid protein antagonizes IFN-beta response by targeting initial step of IFN-beta induction pathway, and its C-terminal region is critical for the antagonism 期刊论文 Lu Xiaolu;Pan Ji';an;Tao Jiali;Pan Ji';an;Guo Deyin
3 Structure-Function Analysis of Severe Acute Respiratory Syndrome Coronavirus RNA Cap Guanine-N7-Methyltransferase 期刊论文 Chen Yu;Tao Jiali;Sun Ying;Wu Andong;Su Ceyang;Gao Guozhen;Cai Hui;Qiu Su;Wu Yingliang;Ahola Tero;Guo Deyin
4 The SUMOylation of zinc-fingers and homeoboxes 1 (ZHX1) by Ubc9 regulates its stability and transcriptionalrepression activity 期刊论文 Shuliang Chen;Xiao Yu;Quan Lei;Lixin Ma;Deyin Guo
5 A specific cytotoxic T-lymphocyte epitope presentation system for antitumor immunity 期刊论文 Sun, Meiyi|Guo, Deyin|Wu, Ying|Shen, Hexiao|Gao, Bin|Liu, Changzhen|
6 Comparative Studies of Various Artificial microRNA Expression Vectors for RNAi in Mammalian Cells 期刊论文 Hu Tao;Chen Ping;Fu Qiong;Liu Ye;Ishaq Musarat;Li Junwei;Ma Li;Guo Deyin
7 Innate immune responses in human monocyte-derived dendritic cells are highly dependent on the size and the 5' phosphorylation of RNA molecules 期刊论文 Miao Jiang;Pamela O¨ sterlund;L. Peter Sarin;Minna M. Poranen;Dennis H. Bamford;Deyin Guo;Ilkka Julkunen
8 Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP 期刊论文 Jin Xu;Chen Yu;Sun Ying;Zeng Cong;Wang Yi;Tao Jiali;Wu Andong;Yu Xiao;Zhang Zhou;Tian Jie;Guo Deyin
9 Short peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2 '-O-methyltransferase activity of nsp10/nsp16 complex 期刊论文 Guo, Deyin|Chen, Yu|Wu, Andong|Sun, Ying|Su, Ceyang|Wu, Hao|Jin, Xu|Tao, Jiali|Wang, Yi|
10 Inhibition of HIV-1 Transcription and Replication by a Newly Identified Cyclin T1 Splice Variant 期刊论文 Gao Guozhen;Wu Xiaoyun;Zhou Jieqiong;He Mingfeng;He Johnny J.;Guo Deyin
11 Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2’-O-methylation by nsp16/nsp10 protein complex 期刊论文 Yu Chen|Ceyang Su|Xinqi Liu|Deyin Guo|
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