细胞命运决定的分子网络

30821065
2008
C05.生物物理与生物化学
李林
创新研究群体项目
研究员
中国科学院上海营养与健康研究所
500万元
信号网络;蛋白质组学;干细胞定向;细胞增殖与分化
2009-01至2011-12
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes. 期刊论文
2 Identification of a small molecule activator of novel PKCs for promoting glucose-dependent insulin secretion 期刊论文 Han Shuai;Pan Heling;Zhang Jianhua;Tan Li;Ma Dawei;Yuan Junying;Wu Jia-Rui
3 Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5 期刊论文
4 High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans 期刊论文 Xing-Jun Cao;Jie Dai;Hao Xu;Song Nie;Xiao Chang;Bao-Yu Hu;Quan-Hu Sheng;Lian-Shui Wang;Zhi-Bin Ning;Yi-Xue Li;Xiao-Kui Guo;Guo-Ping Zhao;Rong Zeng
5 Krüppel-like factor KLF9 regulates PPARγ transactivation at the middle stage of adipogenesis 期刊论文
6 Nuclear Factor of Activated T Cells (NFAT) Proteins Repress Canonical Wnt Signaling via Its Interaction with Dishevelled (Dvl) Protein and Participate in Regulating Neural ProgenitorCell Proliferation and Differentiation 期刊论文
7 Palmitate impairs cytokinesis associated with RhoA inhibition 期刊论文
8 Adipogenesis licensing and execution are disparately linked to cell proliferation 期刊论文 Guo Wei;Zhang Kun-Ming;Tu Kang;Li Yi-Xue;Zhu Li;Xiao Hua-Sheng;Yang Ying;Wu Jia-Rui
9 The TAK1-JNK cascade is required for IRF3 function in the innate immune response 期刊论文 Zhang Bianhong;Li Meng;Chen Liang;Yang Kai;Shan Yufei;Zhu Lianhui;Sun Shaogang;Li Lin;Wang Chen
10 Concurrent quantification of proteome and phosphoproteome to reveal system-wide association of protein phosphorylation and gene expression 期刊论文 Yibo Wu;Jie Dai;Xinglin Yang;Sujun Li;Shilin Zhao;Quanhu Sheng;Jiashu Tang;Guangyong Zheng;Yixue Li;Jiarui Wu;Rong Zeng
11 The differential protein and lipid compositions of noncaveolar lipid microdomains and caveolae 期刊论文 Yao Yao;Hong Shangyu;Zhou Hu;Yuan Taichang;Zeng Rong;Liao Kan
12 Fully-automatic Separation and Identification of Phosphopeptides by Continuous pH-Gradient Anion Exchange Online Coupled with Reversed-Phase Liquid Chromatography Mass Spectrometry. 期刊论文
13 Quantitative detection of single amino-acid polymorphisms by targeted proteomics 期刊论文
14 Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl 期刊论文
15 Quantitative analysis of secretome from adipocytes regulated by insulin 期刊论文
16 TAB2 scaffolds TAK1 and NLK in repressing canonical Wnt signaling 期刊论文
17 A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/(-catenin signaling and colon cancer cell tumorigenesis 期刊论文
18 Identification of zinc-finger bed domain containing 3 (ZBED3) as a novel axin-interacting protein that activates Wnt/(-catenin signaling 期刊论文
19 Different developmental potential of pluripotent stem cells generated by different reprogramming strategies 期刊论文 Shi, Linyu|Jiang, Jing|Lin, Jiangwei|Xiao, Huasheng|Ding, Guohui|Zhang, Man|Yang, Hui|Pei, Gang|Lv, Wenjian|Li, Yixue|Wu, Jiarui|Li, Jinsong|
20 Proteome, phosphoproteome and hydroxyproteome of liver mitochondria in diabetic rats at early pathogenic stages 期刊论文
21 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-?-dependent and mediated by the caspase-3-dependent apoptotic pathway. 期刊论文
22 Comprehensive profiling of phosphopeptides based on anion exchange followed by flow-through enrichment with titanium dioxide (AFET) 期刊论文
23 Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA 期刊论文 Yu-Fei He;Bin-Zhong Li;Zheng Li;Peng Liu;Yang Wang;Qingyu Tang;Jianping Ding;Yingying Jia;Zhangcheng Chen;Lin Li;Yan Sun;Xiuxue Li;Qing Dai;Chun-Xiao Song;Kangling Zhang;Chuan He;Guo-Liang Xu
24 Effect of peptide-to-TiO2 beads ratio on phosphopeptide enrichment Selectivity 期刊论文
25 Large-scale phosphoproteome profiles comprehensive features of mouse embryonic stem cells 期刊论文
26 Chk1 prevents abnormal mitosis of S-phase HeLa cells containing DNA damage 期刊论文 Li XiaoFang;Ward Tarsha;Yao XueBiao;Wu JiaRui
27 Coevolution is a short-distance force at the protein interaction level and correlates with the modular organization of protein networks 期刊论文 Liang Zhi;Xu Meng;Teng Maikun;Niu Liwen;Wu Jiarui
28 B23 interacts with PES1 and is involved in nucleolar localization of PES1 期刊论文
29 microRNA-16 expression in HeLa cells is upregulated in cell-cycle and drug dependent manner 期刊论文
30 Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation 期刊论文 Zhenfei Li|Fen Nie|Sheng Wang|Lin Li|
31 Berberine promotes the development of atherosclerosis and foam cell formation by inducing scavenger receptor A expression in macrophage 期刊论文
32 CIN85 associated with endosomal membranes and phosphatidic acid 期刊论文
33 Micropinocytosis contributes to the macrophage foam cell formation in RAW264.7 cells. 期刊论文
34 Enzymatic preparation of an artificial microRNA library 期刊论文
35 JAK2/STAT3 pathway is involved in the early stage of adipogenesis through regulating C/EBP( transcription 期刊论文
36 Temporal and spatial profiling of nuclei-associated proteins upon TNF-alpha/NF-kappaB signaling 期刊论文
37 Dishevelled interacts with p65 and acts as a repressor of NF-(B-mediated transcription. 期刊论文
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